Area of research
Genetics · Epidemiology
Research interest
Research interests include Biology, Ulcerative colitis, Inflammatory bowel disease, Medicine, Disease, and Genome-wide association study.
Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
Infliximab versus ciclosporin for steroid-resistant acute severe ulcerative colitis (CONSTRUCT): a mixed methods, open-label, pragmatic randomised trial
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Association Between Response to Etrolizumab and Expression of Integrin αE and Granzyme A in Colon Biopsies of Patients With Ulcerative Colitis
Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes
Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial
HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis