Area of research
Pharmaceutical Science · Gastroenterology
Research interest
Research interests include Chemistry, Pharmacology, Medicine, In vivo, Drug, and Posaconazole.
Comparative Evaluation of Dissolution Performance in a USP 2 Setup and Alternative Stirrers and Vessel Designs: A Systematic Computational Investigation
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity
A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP
Unraveling the behavior of oral drug products inside the human gastrointestinal tract using the aspiration technique: History, methodology and applications
The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group
Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration
Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in vivo approach
Application of a Dynamic Fluid and pH Model to Simulate Intraluminal and Systemic Concentrations of a Weak Base in GastroPlus™
Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’ project
Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate–CO<sub>2</sub> Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical Significance
Persistent Threats by Persistent Pollutants: Chemical Nature, Concerns and Future Policy Regarding PCBs—What Are We Heading For?
<i>In Silico</i> Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole
Exploring gastrointestinal variables affecting drug and formulation behavior: Methodologies, challenges and opportunities
Gastrointestinal and Systemic Monitoring of Posaconazole in Humans After Fasted and Fed State Administration of a Solid Dispersion
Bile Salt Micelles and Phospholipid Vesicles Present in Simulated and Human Intestinal Fluids: Structural Analysis by Flow Field–Flow Fractionation/Multiangle Laser Light Scattering
Supersaturation and Precipitation of Posaconazole Upon Entry in the Upper Small Intestine in Humans
Gastrointestinal behavior of nano- and microsized fenofibrate: In vivo evaluation in man and in vitro simulation by assessment of the permeation potential
Gastrointestinal transfer: In vivo evaluation and implementation in in vitro and in silico predictive tools
A review of drug solubility in human intestinal fluids: Implications for the prediction of oral absorption
Supersaturation in human gastric fluids