Area of research
Molecular Biology · Neurology
Research interest
Research interests include Retinal Development and Disorders, Neuroinflammation and Neurodegeneration Mechanisms, Connexins and lens biology, and Traumatic Brain Injury and Neurovascular Disturbances.
Genetic ablation of the TET family in retinal progenitor cells impairs photoreceptor development and leads to blindness
Accumulation of Epigenetic Noise in the Aging Corneal Epithelium and Its Possible Mechanism
Various Forms of Programmed Cell Death Are Concurrently Activated in the Population of Retinal Ganglion Cells after Ischemia and Reperfusion
Molecular mechanisms of NMDA excitotoxicity in the retina
Multiple types of programmed necrosis such as necroptosis, pyroptosis, oxytosis/ferroptosis, and parthanatos contribute simultaneously to retinal damage after ischemia–reperfusion
The Potential Role of Epigenetic Mechanisms in the Development of Retinitis Pigmentosa and Related Photoreceptor Dystrophies
The effect of extrinsic Wnt/β‐catenin signaling in Muller glia on retinal ganglion cell neurite growth
Mitochondrial targeted therapy with elamipretide (MTP-131) as an adjunct to tumor necrosis factor inhibition for traumatic optic neuropathy in the acute setting
Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury
The epigenetic basis for the impaired ability of adult murine retinal pigment epithelium cells to regenerate retinal tissue
DNA Methylation Dynamics During the Differentiation of Retinal Progenitor Cells Into Retinal Neurons Reveal a Role for the DNA Demethylation Pathway
Development and epigenetic plasticity of murine Müller glia
Wnt signaling induces neurite outgrowth in mouse retinal ganglion cells
Tumor Necrosis Factor Inhibition in the Acute Management of Traumatic Optic Neuropathy
Pannexin 1 sustains the electrophysiological responsiveness of retinal ganglion cells
A Novel Mouse Model of Traumatic Optic Neuropathy Using External Ultrasound Energy to Achieve Focal, Indirect Optic Nerve Injury
Mitochondrial DNA Double-Strand Breaks in Oligodendrocytes Cause Demyelination, Axonal Injury, and CNS Inflammation
Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis
Virally delivered, constitutively active <scp>NF</scp>κB improves survival of injured retinal ganglion cells
Molecular Characterization of Notch1 Positive Progenitor Cells in the Developing Retina
Retinal ganglion cell (RGC) programmed necrosis contributes to ischemia–reperfusion-induced retinal damage
Tumor necrosis factor‐alpha mediates activation of <scp>NF</scp>‐κB and <scp>JNK</scp> signaling cascades in retinal ganglion cells and astrocytes in opposite ways
Putative role of protein kinase C in neurotoxic inflammation mediated by extracellular heat shock protein 70 after ischemia-reperfusion
Cellular Mechanisms of High Mobility Group 1 (HMGB-1) Protein Action in the Diabetic Retinopathy
The <scp>TIR</scp>‐domain‐containing adapter inducing interferon‐β‐dependent signaling cascade plays a crucial role in ischemia–reperfusion‐induced retinal injury, whereas the contribution of the myeloid differentiation primary response 88‐dependent signaling cascade is not as pivotal
Correction: Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning
Pannexin1 Stabilizes Synaptic Plasticity and Is Needed for Learning
Genetic Ablation of Pannexin1 Protects Retinal Neurons from Ischemic Injury
Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis
β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival