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Gary Middleton

University of Oxford · GB
Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Colorectal Cancer Treatments and Studies, Lung Cancer Treatments and Mutations, and Cancer Genomics and Diagnostics.
h-index
69
citations
29,414
works
457
NIH funding
primary concept
Medicine
email

Recent publications

Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology.
2026cited by 0position: contributordoi
Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma
Nature Medicine 2025cited by 75position: middledoi
The impact of the immunological context on outcomes of solid cancer patients treated with genotype-matched targeted therapies: a comprehensive review.
2025cited by 1position: contributordoi
Figure 3 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Supplementary Tables S1 - S5 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Figure 6 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Figure 5 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Figure 4 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Figure 2 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Figure 1 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Supplementary Fig. S1 - S12 from Tissue-Resident Memory T Cells in Pancreatic Ductal Adenocarcinoma Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade
2025cited by 0position: contributordoi
Neoadjuvant immunotherapy for dMMR and pMMR colorectal cancers: therapeutic strategies and putative biomarkers of response
Nature Reviews Clinical Oncology 2024cited by 63position: middledoi
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
Nature Communications 2024cited by 42position: middledoi
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma.
2024cited by 27position: contributordoi
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models
Nature Communications 2024cited by 25position: middledoi
Pancreatic Adenocarcinoma: Long-Term Outcomes of Adjuvant Therapy in the ESPAC4 Phase III Trial
Journal of Clinical Oncology 2024cited by 19position: middledoi
The potential clinical utility of Whole Genome Sequencing for patients with cancer: evaluation of a regional implementation of the 100,000 Genomes Project.
2024cited by 8position: contributordoi
Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx.
2024cited by 3position: contributordoi
A clinical trial assessing the addition of continuous ketogenic diet therapy to standard chemotherapy and immunotherapy treatment for patients with advanced squamous cell lung cancer
http://isrctn.com/ 2024cited by 1position: contributordoi
Lung adenocarcinoma promotion by air pollutants.
2023cited by 521position: contributordoi
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
Nature 2023cited by 327position: middledoi
The evolution of lung cancer and impact of subclonal selection in TRACERx
Nature 2023cited by 300position: middledoi
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
2023cited by 260position: contributordoi
The evolution of lung cancer and impact of subclonal selection in TRACERx.
2023cited by 233position: contributordoi
The evolution of non-small cell lung cancer metastases in TRACERx
Nature 2023cited by 230position: middledoi
Antibodies against endogenous retroviruses promote lung cancer immunotherapy.
2023cited by 215position: contributordoi
The evolution of non-small cell lung cancer metastases in TRACERx.
2023cited by 177position: contributordoi
Genomic-transcriptomic evolution in lung cancer and metastasis.
2023cited by 175position: contributordoi
Body composition and lung cancer-associated cachexia in TRACERx
Nature Medicine 2023cited by 123position: middledoi
SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease.
2023cited by 108position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 77 papers (2020–2026)Andrew D. Beggs · Birmingham City University51 papers (2019–2026) · 47 papers (2019–2026) · 39 papers (2022–2023)Philippe Tanière · University Hospitals Birmingham NHS Foundation Trust38 papers (2023–2023)Celina M. Whalley · University of Birmingham38 papers (2023–2023) · 38 papers (2023–2023)Neeraj Lal · University of Birmingham38 papers (2023–2023)Kasun Wanigasooriya · University Hospitals Birmingham NHS Foundation Trust38 papers (2023–2023) · 38 papers (2023–2023)Anetta Ptasinska · University of Birmingham38 papers (2023–2023)Claudia M. A. Pinna · Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico38 papers (2023–2023)Claire Bryer · University of Birmingham38 papers (2023–2023)Oliver J. Pickles · Queen Elizabeth Hospital Birmingham38 papers (2023–2023)Nahla Elzefzafy · Birmingham Dental Hospital38 papers (2023–2023)Louise Tee · Birmingham Dental Hospital38 papers (2023–2023)Paul Moss · Imperial College London22 papers (2020–2025)Wayne Croft · The University of Birmingham21 papers (2023–2025)Francesca Marcon · Istituto Superiore di Sanità21 papers (2023–2025)Sandra Margielewska-Davies · Jagiellonian University21 papers (2023–2025)