Area of research
Cellular and Molecular Neuroscience · Physiology
Research interest
Research interests include Antibody, Tau protein, Epitope, In vivo, Internalization, and Endocytosis.
Dynamic assessment of tau immunotherapies in the brains of live animals by two-photon imaging
Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy
Antibody Uptake into Neurons Occurs Primarily via Clathrin-dependent Fcγ Receptor Endocytosis and Is a Prerequisite for Acute Tau Protein Clearance
Two Novel Tau Antibodies Targeting the 396/404 Region Are Primarily Taken Up by Neurons and Reduce Tau Protein Pathology