Area of research
Cognitive Neuroscience · Radiology, Nuclear Medicine and Imaging
Research interest
Research topics from publications: Decreased Complexity in Alzheimer's Disease: Resting-State fMRI Evidence of Brain Entropy Mapping; Abnormal Anatomical Rich-Club Organization and Structural–Functional Coupling in Mild Cognitive Impairment and Alzheimer's Disease; Resting-state functional connectivity abnormalities in first-onset unmedicated depression; Machine Learning Classification Combining Multiple Features of A Hyper-Network of fMRI Data in Alzheimer's Disease; Sex Differences in Anatomical Rich-Club and Structural–Functional Coupling in the Human Brain Network; Dynamic Complexity of Spontaneous BOLD Activity in Alzheimer’s Disease and Mild Cognitive Impairment Using Multiscale Entropy Analysis; Alzheimer Classification Using a Minimum Spanning Tree of High-Order Functional Network on fMRI Dataset; Reduced hemispheric asymmetry of brain anatomical networks in attention deficit hyperactivity disorder; Hemisphere and Gender Differences in the Rich-Club Organization of Structural Networks; Resting-State Brain Functional Hyper-Network Construction Based on Elastic Net and Group Lasso Methods. Representative work: Alzheimer's disease (AD) is a frequently observed, irreversible brain function disorder among elderly individuals. Resting-state functional magnetic resonance imaging (rs-fMRI) has been introduced as an alternative approach to assessing brain functional abnormalities in AD patients. However, alterations in the brain rs-fMRI signal complexities in mild cognitive impairment (MCI) and AD patients remain unclear. Here, we described the novel application of permutation entropy (PE) to investigate the abnormal complexity of rs-fMRI signals in MCI and AD patients. The rs-fMRI signals of 30 normal controls (NCs), 33 early MCI (EMCI), 32 late MCI (LMCI), and 29 AD patients were obtained from the Alzh Emerging research indicates interruptions in the wiring organization of the brain network in Mild cognitive impairment (MCI) and Alzheimer's disease (AD). Due to the important role of rich-club organization in distinguishing abnormalities of AD patients and the close relationship between structural connectivity (SC) and functional connectivity (FC), our study examined whether changes in SC-FC coupling and the relationship with abnormal rich-club organizations during the development of diseases may contribute to the pathophysiology of AD. Structural diffusion-
Deep Learning for Epileptic Seizure Detection Using a Causal-Spatio-Temporal Model Based on Transfer Entropy
Seizure Pathways Changes at the Subject-Specific Level via Dynamic Step Effective Network Analysis
The attention network characteristics of adults with high ADHD traits: low stability, boost accuracy by sacrificing response time
Beta-informativeness-diffusion multilayer graph embedding for brain network analysis
Alzheimer’s Disease: Insights from Large-Scale Brain Dynamics Models
Effects of virtual lesions on temporal dynamics in cortical networks based on personalized dynamic models
Alterations in white matter network dynamics in patients with schizophrenia and bipolar disorder
Reduced Modular Segregation of White Matter Brain Networks in Attention Deficit Hyperactivity Disorder
Altered Complexity of Spontaneous Brain Activity in Schizophrenia and Bipolar Disorder Patients
Multiple Survival Outcome Prediction of Glioblastoma Patients Based on Multiparametric MRI
Attention Field Size Alters Patterns of Population Receptive Fields in the Early Visual Cortex
Abnormal Anatomical Rich-Club Organization and Structural–Functional Coupling in Mild Cognitive Impairment and Alzheimer's Disease
Sex Differences in Anatomical Rich-Club and Structural–Functional Coupling in the Human Brain Network
APOE ε4 and cognitive reserve effects on the functional network in the Alzheimer’s disease spectrum
Abnormalities in hemispheric lateralization of intra- and inter-hemispheric white matter connections in schizophrenia
Phosphodiesterase 4D Gene Modifies the Functional Network of Patients With Mild Cognitive Impairment and Alzheimer’s Disease
Disrupted Rich Club Organization of Hemispheric White Matter Networks in Bipolar Disorder
Hemisphere and Gender Differences in the Rich-Club Organization of Structural Networks
Abnormal Entropy Modulation of the EEG Signal in Patients With Schizophrenia During the Auditory Paired-Stimulus Paradigm
Graph-based network analysis of resting-state fMRI: test-retest reliability of binarized and weighted networks
Abnormal Rich Club Organization in Hemispheric White Matter Networks of ADHD
Resting-State Functional Network Scale Effects and Statistical Significance-Based Feature Selection in Machine Learning Classification
Dynamic Complexity of Spontaneous BOLD Activity in Alzheimer’s Disease and Mild Cognitive Impairment Using Multiscale Entropy Analysis
Reduced hemispheric asymmetry of brain anatomical networks in attention deficit hyperactivity disorder
Resting-State Brain Functional Hyper-Network Construction Based on Elastic Net and Group Lasso Methods
The Abnormality of Topological Asymmetry in Hemispheric Brain Anatomical Networks in Bipolar Disorder
Abnormal Functional Brain Networks in Mild Cognitive Impairment and Alzheimer’s Disease: A Minimum Spanning Tree Analysis
fMRI classification method with multiple feature fusion based on minimum spanning tree analysis
Decreased Complexity in Alzheimer's Disease: Resting-State fMRI Evidence of Brain Entropy Mapping
Machine Learning Classification Combining Multiple Features of A Hyper-Network of fMRI Data in Alzheimer's Disease