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Henry Lee-Six

University of Cambridge · GB
Area of research
Cancer Research · Pathology and Forensic Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Genetic factors in colorectal cancer, Colorectal Cancer Treatments and Studies, and Lung Cancer Treatments and Mutations.
h-index
46
citations
21,619
works
163
NIH funding
primary concept
Biology
email

Recent publications

The earliest stages of neoplastic transformation in Familial Adenomatous Polyposis
Research Square 2025cited by 1position: middledoi
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
Nature Biotechnology 2024cited by 9position: middledoi
APOBEC mutagenesis is a common process in normal human small intestine
Nature Genetics 2023cited by 62position: middledoi
Targetable NOTCH1 rearrangements in reninoma
Nature Communications 2023cited by 12position: middledoi
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
Nature Communications 2022cited by 61position: middledoi
Author Correction: Inferring structural variant cancer cell fraction
Nature Communications 2022cited by 0position: middledoi
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Nature Communications 2022cited by 0position: middledoi
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Cell 2021cited by 550position: middledoi
Discovery and Features of an Alkylating Signature in Colorectal Cancer
Cancer Discovery 2021cited by 77position: middledoi
Inherited <i>MUTYH</i> mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
bioRxiv (Cold Spring Harbor Laboratory) 2021cited by 3position: middledoi
The evolutionary history of 2,658 cancers
Nature 2020cited by 1,117position: middledoi
Inferring structural variant cancer cell fraction
Nature Communications 2020cited by 56position: middledoi
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Nature Communications 2020cited by 50position: middledoi
Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions
Nature Medicine 2019cited by 278position: middledoi
Intra-tumour diversification in colorectal cancer at the single-cell level
Nature 2018cited by 564position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Michael R. Stratton · Colon and Rectal Surgery Associates3 papers (2018–2023)Tim Coorens · Broad Institute3 papers (2021–2023)Peter J. Campbell · Quotient Clinical (United Kingdom)3 papers (2018–2023)Kourosh Saeb‐Parsy · University of Cambridge2 papers (2021–2023)Sam Behjati · Wellcome Sanger Institute2 papers (2018–2023)Mathijs A. Sanders · Vanderbilt University2 papers (2021–2023)Thomas J. Mitchell · Maine Farmland Trust2 papers (2018–2023)Matthew D. Young · Wellcome Sanger Institute2 papers (2018–2023)Simon Rushbrook · Norfolk and Norwich University Hospitals NHS Foundation Trust2 papers (2021–2023)Hyunchul Jung · Ulsan College2 papers (2021–2023)Iñigo Martincorena · Wellcome Sanger Institute2 papers (2021–2023) · 2 papers (2021–2023)Simon J. A. Buczacki · Cambridge University Hospitals NHS Foundation Trust2 papers (2021–2023) · 2 papers (2021–2023)Julian R. Sampson · Cardiff University1 papers (2021–2021)Edward L. Giovannucci · Harvard University1 papers (2021–2021)Philip H. Jones · The University of Texas MD Anderson Cancer Center1 papers (2023–2023)Eliezer M. Van Allen · Harvard University1 papers (2021–2021) · 1 papers (2023–2023)Christopher Alder · Guy's and St Thomas' NHS Foundation Trust1 papers (2018–2018)