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David W. Speicher

The Wistar Institute · US
🔎 Find collaborators in Spectroscopy · Physiology →
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Area of research
Spectroscopy · Physiology
Research interest
Research interests include Advanced Proteomics Techniques and Applications, Erythrocyte Function and Pathophysiology, Mass Spectrometry Techniques and Applications, and Histone Deacetylase Inhibitors Research.
h-index
86
citations
28,875
works
614
NIH funding
primary concept
Chemistry
email

Recent publications

Author Correction: Stromal changes in the aged lung induce an emergence from melanoma dormancy
Nature 2025cited by 3position: middledoi
Supplemental Figure 3 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025cited by 0position: contributordoi
Supplementary Data Tables S1-S2 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2025cited by 0position: contributordoi
Data from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025cited by 0position: contributordoi
Supplemental Figure 2 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025cited by 0position: contributordoi
Supplemental Figure 1 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025cited by 0position: contributordoi
Supplementary Data Figures S1-S5 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2025cited by 0position: contributordoi
Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity
Nature Communications 2024cited by 21position: middledoi
Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis.
2024cited by 11position: contributordoi
Supplemental Figure 3 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Supplemental Figure 2 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Supplemental Figure 1 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Supplemental Figure 3 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Data from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Supplemental Figure 1 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Supplemental Figure 2 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024cited by 0position: contributordoi
Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition.
2023cited by 27position: contributordoi
Supplementary Data Tables S1-S2 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2023cited by 0position: contributordoi
Data from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2023cited by 0position: contributordoi
Data from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2023cited by 0position: contributordoi
Supplementary Data Tables S1-S2 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2023cited by 0position: contributordoi
Supplementary Data Figures S1-S5 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2023cited by 0position: contributordoi
Supplementary Data Figures S1-S5 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2023cited by 0position: contributordoi
Stromal changes in the aged lung induce an emergence from melanoma dormancy
Nature 2022cited by 175position: middledoi
Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy
Breast Cancer Research 2021cited by 68position: middledoi
Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2
Cancer Discovery 2020cited by 150position: middledoi
BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors
Oncogene 2020cited by 48position: middledoi
NAD+ metabolism governs the proinflammatory senescence-associated secretome
Nature Cell Biology 2019cited by 388position: middledoi
Aberrant splicing contributes to severe α-spectrin–linked congenital hemolytic anemia
Journal of Clinical Investigation 2019cited by 33position: middledoi
Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors
Cancer Cell 2017cited by 643position: middledoi

Grants

Renovation of Wistar Structural Biology Macromolecular Interactions Complex
NSF9602834$267,0841996–1998PIRePORTER
Structure-Function Analysis of Alpha-Actinin Assembly
NSF9304746$274,0001993–1997PIRePORTER

Frequent collaborators

· 21 papers (2023–2025)Hsin‐Yao Tang · The Wistar Institute19 papers (2015–2025)Murilo R. Rocha · Johns Hopkins University12 papers (2024–2025)Denis Wirtz · University of Pennsylvania12 papers (2024–2025)Mitchell E. Fane · Sidney Kimmel Comprehensive Cancer Center12 papers (2024–2025)Marie E. Portuallo · Johns Hopkins University12 papers (2024–2025)Vito W. Rebecca · Sidney Kimmel Comprehensive Cancer Center12 papers (2024–2025)Andrew Kossenkov · Computational Physics (United States)12 papers (2024–2025)Agrani Dixit · Yale University12 papers (2024–2025)Reeti Behera · The Wistar Institute12 papers (2024–2025)Alexis E. Carey · Clark Atlanta University12 papers (2024–2025)Vania Wang · Sidney Kimmel Cancer Center12 papers (2024–2025)Ashani Weeraratna · Cancer Clinic12 papers (2024–2025) · 12 papers (2024–2025) · 12 papers (2024–2025)Gretchen M. Alicea · Johns Hopkins University12 papers (2024–2025)Payal Patel · 12 papers (2024–2025)Meihan Wei · Cornell University12 papers (2024–2025)Phyllis A. Gimotty · California University of Pennsylvania11 papers (2013–2025)Aleksandra Zivkovic · Heinrich Heine University Düsseldorf9 papers (2023–2025)
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