Area of research
Molecular Biology · Hematology
Research interest
Research interests include Gut microbiota and health, Hematopoietic Stem Cell Transplantation, Immune Cell Function and Interaction, and Clostridium difficile and Clostridium perfringens research.
The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration
A microbial metabolite protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration
Mucosal calprotectin is associated with severity of aGI-GVHD and poor outcomes after allogeneic stem cell transplantation
Multi-faceted influence of immunomodulatory metabolites on CAR-T cell therapy
Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease
Immunomodulatory Microbial Metabolites Protect Against Graft-Vs-Host Disease and Enhance Anti-Leukemia Responses in Mice and Patients Receiving Stem Cell Transplantation
The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitors
Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans
Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis