Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Genetic Neurodegenerative Diseases, Protein Structure and Dynamics, Mitochondrial Function and Pathology, and Enzyme Structure and Function.
Molecular Crowding: The History and Development of a Scientific Paradigm
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS
RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding
Thrombocytopenia 4 (<scp>THC4</scp>): Six novel families with mutations of the cytochrome c gene
The structural properties of full-length annexin A11
SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy
Probing TDP-43 condensation using an in silico designed aptamer
The Protein Unfolded State: One, No One and One Hundred Thousand
Biallelic variants in HECT E3 paralogs, HECTD4 and UBE3C, encoding ubiquitin ligases cause neurodevelopmental disorders that overlap with Angelman syndrome
The Wide World of Coacervates: From the Sea to Neurodegeneration
Why does the Aβ peptide of Alzheimer share structural similarity with antimicrobial peptides?
RNA as the stone guest of protein aggregation
RRM adjacent TARDBP mutations disrupt RNA binding and enhance TDP-43 proteinopathy
RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43
On the mechanism of calcium‐dependent activation of NADPH oxidase 5 (NOX5)
Protein Structural Information and Evolutionary Landscape by In Vitro Evolution
Recombinant mussel protein Pvfp-5β: A potential tissue bioadhesive
The RNA-Recognition Motifs of TAR DNA-Binding Protein 43 May Play a Role in the Aberrant Self-Assembly of the Protein
Glycation affects fibril formation of Aβ peptides
Rv1460, a SufR homologue, is a repressor of the suf operon in Mycobacterium tuberculosis
Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model
The cold denaturation of IscU highlights structure–function dualism in marginally stable proteins
The Molecular Bases of the Dual Regulation of Bacterial Iron Sulfur Cluster Biogenesis by CyaY and IscX
The role of oxidative stress in Friedreich's ataxia
Thrombopoietin mutation in congenital amegakaryocytic thrombocytopenia treatable with romiplostim
An optimized strategy to measure protein stability highlights differences between cold and hot unfolded states
The Emperor's new clothes: Myths and truths of in-cell NMR
Expression and Purification of ZASP Subdomains and Clinically Important Isoforms: High-Affinity Binding to G-Actin
Interplay of histidine residues of the Alzheimer’s disease Aβ peptide governs its Zn-induced oligomerization
The Ball and Chain of Polyubiquitin Structures