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John V. Pearson

QIMR Berghofer Medical Research Institute · AU
Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Genomics and Diagnostics, Pancreatic and Hepatic Oncology Research, Melanoma and MAPK Pathways, and Ovarian cancer diagnosis and treatment.
h-index
77
citations
56,967
works
402
NIH funding
primary concept
Medicine
email

Recent publications

Explainable machine learning identifies features and thresholds predictive of immunotherapy response
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 1position: middledoi
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer
Nature Cancer 2023cited by 119position: middledoi
Australian Genomics: Outcomes of a 5-year national program to accelerate the integration of genomics in healthcare
The American Journal of Human Genetics 2023cited by 67position: middledoi
Heritable defects in telomere and mitotic function selectively predispose to sarcomas
Science 2023cited by 43position: middledoi
Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics 2023cited by 5position: middledoi
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature Genetics 2023cited by 4position: middledoi
Data from Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes
2023cited by 0position: middledoi
Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
Cancer Discovery 2022cited by 104position: middledoi
Anatomic position determines oncogenic specificity in melanoma
Nature 2022cited by 96position: middledoi
Shariant platform: Enabling evidence sharing across Australian clinical genetic-testing laboratories to support variant interpretation
The American Journal of Human Genetics 2022cited by 33position: middledoi
Gene-Expression Profiling of Mucinous Ovarian Tumors and Comparison with Upper and Lower Gastrointestinal Tumors Identifies Markers Associated with Adverse Outcomes
Clinical Cancer Research 2022cited by 21position: middledoi
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer
Nature Communications 2022cited by 0position: middledoi
Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordance
Cancer Cell 2021cited by 162position: middledoi
Patterns of somatic structural variation in human cancer genomes
Nature 2020cited by 979position: middledoi
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics 2020cited by 765position: middledoi
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature Genetics 2020cited by 472position: middledoi
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Nature Genetics 2020cited by 305position: middledoi
Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity
Nature Communications 2020cited by 178position: middledoi
Whole genome landscapes of uveal melanoma show an ultraviolet radiation signature in iris tumours
Nature Communications 2020cited by 142position: middledoi
Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Nature Genetics 2020cited by 13position: middledoi
Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets
Nature Communications 2019cited by 335position: middledoi
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan
Nature Communications 2019cited by 258position: middledoi
Molecular Genomic Profiling of Melanocytic Nevi
Journal of Investigative Dermatology 2019cited by 75position: middledoi
Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas
Cellular and Molecular Gastroenterology and Hepatology 2019cited by 59position: middledoi
Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications
The Journal of Pathology 2018cited by 98position: middledoi
Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility
International Journal of Cancer 2018cited by 58position: middledoi
Telomere sequence content can be used to determine ALT activity in tumours
Nucleic Acids Research 2018cited by 52position: middledoi
Whole-genome landscapes of major melanoma subtypes
Nature 2017cited by 1,478position: middledoi
<i>EIF1AX</i> and <i>NRAS</i> Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas
Cancer Research 2017cited by 89position: middledoi
Lost in translation: returning germline genetic results in genome-scale cancer research
Genome Medicine 2017cited by 83position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Nicola Waddell · QIMR Berghofer Medical Research Institute8 papers (2012–2025)Sean M. Grimmond · University of Chicago3 papers (2012–2018)Nicholas K. Hayward · QIMR Berghofer Medical Research Institute3 papers (2017–2019)Peter A. Johansson · QIMR Berghofer Medical Research Institute3 papers (2017–2019)Stephen H. Kazakoff · QIMR Berghofer Medical Research Institute3 papers (2016–2019)Richard A. Scolyer · Westmead Institute for Medical Research3 papers (2017–2019)Kátia Nones · The University of Queensland3 papers (2012–2019)Graham J. Mann · Murdoch University3 papers (2017–2019)James S. Wilmott · University of Sydney3 papers (2017–2019)Ann‐Marie Patch · QIMR Berghofer Medical Research Institute3 papers (2017–2019)Conrad Leonard · QIMR Berghofer Medical Research Institute2 papers (2012–2025)Scott Wood · University of Leeds2 papers (2012–2025)Felicity Newell · QIMR Berghofer Medical Research Institute2 papers (2012–2019)Marina Pajic · Garvan Institute of Medical Research2 papers (2012–2017)Mark J. Cowley · Garvan Institute of Medical Research2 papers (2012–2017)Andrew V. Biankin · University of Glasgow2 papers (2012–2017)Oliver Holmes · QIMR Berghofer Medical Research Institute2 papers (2012–2018)Mark Pinese · Garvan Institute of Medical Research2 papers (2012–2017)John F. Thompson · Kaiser Permanente Center for Health Research2 papers (2017–2019)David S. Miller · Gynecologic Oncology Group2 papers (2012–2017)