Area of research
Molecular Biology · Oncology
Research interest
Research interests include Heat shock proteins research, Cancer-related Molecular Pathways, Protein Structure and Dynamics, and RNA modifications and cancer.
Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
Adhesion-mediated mechanosignaling forces mitohormesis
Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels
Zika Virus Dependence on Host Hsp70 Provides a Protective Strategy against Infection and Disease
Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor
Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein–Protein Interactions with Heat Shock Protein 70 (Hsp70)
Inhibitors and chemical probes for molecular chaperone networks
A Local Allosteric Network in Heat Shock Protein 70 (Hsp70) Links Inhibitor Binding to Enzyme Activity and Distal Protein–Protein Interactions
Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades
Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70)
Protein Cross-Linking Capillary Electrophoresis for Protein–Protein Interaction Analysis
Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells
Hydrolytic function of Exo1 in mammalian mismatch repair