Area of research
Genetics · Infectious Diseases
Research interest
Research interests include Genetic Associations and Epidemiology, Genomics and Rare Diseases, Inflammatory Bowel Disease, and Genomic variations and chromosomal abnormalities.
Examining the role of common variants in rare neurodevelopmental conditions
HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility
Context-specific emergence and growth of the SARS-CoV-2 Delta variant
COVID-19 due to the B.1.617.2 (Delta) variant compared to B.1.1.7 (Alpha) variant of SARS-CoV-2: a prospective observational cohort study
Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England
Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England
Genomic reconstruction of the SARS-CoV-2 epidemic in England
Genomic reconstruction of the SARS-CoV-2 epidemic in England
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease
Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
De novo mutations in regulatory elements in neurodevelopmental disorders
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
Quantifying the contribution of recessive coding variation to developmental disorders
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
Fine-mapping inflammatory bowel disease loci to single-variant resolution
The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
A reference panel of 64,976 haplotypes for genotype imputation
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers