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Pablo Umaña

Roche (Switzerland) · CH
Area of research
Oncology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Monoclonal and Polyclonal Antibodies Research, CAR-T cell therapy research, Immune Cell Function and Interaction, and Cancer Immunotherapy and Biomarkers.
h-index
51
citations
12,436
works
548
NIH funding
primary concept
Medicine
email

Recent publications

Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma
Blood 2024cited by 25position: lastdoi
The physiological interactome of TCR-like antibody therapeutics in human tissues
Nature Communications 2024cited by 17position: middledoi
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment
Leukemia 2024cited by 8position: middledoi
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
Journal of Clinical Investigation 2023cited by 55position: middledoi
Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade
Clinical Cancer Research 2023cited by 37position: middledoi
Fine Tuning Bispecific Activity in CLL: Harmonizing a CD19/20-T Cell Bispecific with a CD28 or 4-1BBL Costimulatory Bispecific
Blood 2023cited by 2position: middledoi
PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program
Nature 2022cited by 312position: middledoi
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
Nature 2022cited by 256position: lastdoi
RG6234: A Novel 2:1 GPRC5D T Cell Bispecific Antibody Exhibits Best in Class Potential for the Treatment of Multiple Myeloma As a Monotherapy and in Combination
Blood 2022cited by 15position: lastdoi
Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell–Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial
Journal of Clinical Oncology 2021cited by 404position: middledoi
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody
Blood 2021cited by 66position: middledoi
Augmenting Efficacy of T-Cell Bispecific Antibodies in AML through a Tumor Stroma-Targeted 4-1BB Agonist
Blood 2021cited by 2position: middledoi
Targeting Intracellular WT1 in AML Utilizing a T Cell Bispecific Antibody Construct: Augmenting Efficacy through Combination with Lenalidomide
Blood 2019cited by 6position: middledoi
PF207 TARGETING WILMS TUMOR 1 WITH A T CELL BISPECIFIC ANTIBODY (WT1‐TCB): EX VIVO AND IN VIVO POTENCY BY BIVALENT RECOGNITION OF PEPTIDE‐MHC COMPLEXES FROM AN INTRACELLULAR TUMOR ANTIGEN
HemaSphere 2019cited by 0position: middledoi
Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti–Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis
Journal of Nuclear Medicine 2015cited by 107position: middledoi
Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells
Journal of Autoimmunity 2014cited by 87position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Christian Klein · Heidelberg University9 papers (2014–2024)Gerulf Hänel · LMU Klinikum4 papers (2019–2024)Alejandro Carpy · University of Tübingen4 papers (2019–2024)Marion Subklewe · Cancer Research Center4 papers (2019–2024)Veit Bücklein · Cancer Research Center3 papers (2019–2024)Anne-Sophie Neumann · LMU Klinikum3 papers (2021–2024) · 3 papers (2019–2023)Wei Xu · The First Affiliated Hospital, Sun Yat-sen University3 papers (2019–2022)Vesna Pulko · University of Arizona3 papers (2019–2021) · 3 papers (2019–2024) · 3 papers (2019–2024)Koorosh Korfi · University of Glasgow2 papers (2023–2024)Nikola P. Konstandin · LMU Klinikum2 papers (2019–2019) · 2 papers (2014–2015) · 2 papers (2014–2015) · 2 papers (2014–2015)Antje Tunger · German Cancer Research Center2 papers (2019–2019)Marc Schmitz · German Cancer Research Center2 papers (2019–2019)Christian Augsberger · MorphoSys (Germany)2 papers (2019–2019)Christina Heitmüller · Gene Therapy Laboratory2 papers (2019–2019)