Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Ubiquitin and proteasome pathways, CRISPR and Genetic Engineering, Biotin and Related Studies, and Mitochondrial Function and Pathology.
Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
The Genetic Architecture of Congenital Diarrhea and Enteropathy
Recruitment of FBXO22 for targeted degradation of NSD2
Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors
The lysosomal lipid transporter LIMP-2 is part of lysosome–ER STARD3-VAPB-dependent contact sites
Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT
Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity
Recruitment of FBXO22 for Targeted Degradation of NSD2
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate
Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations
An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread
EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation
ProHits-viz: a suite of web tools for visualizing interaction proteomics data
Differential requirements for Tousled-like kinases 1 and 2 in mammalian development
UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119
A global genetic interaction network maps a wiring diagram of cellular function
Data Independent Acquisition analysis in ProHits 4.0
RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
A Strategy for Modulation of Enzymes in the Ubiquitin System
A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen