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H. Léna

Inserm · FR
Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Lung Cancer Treatments and Mutations, Lung Cancer Research Studies, Lung Cancer Diagnosis and Treatment, and Cancer Immunotherapy and Biomarkers.
h-index
30
citations
7,711
works
211
NIH funding
primary concept
Medicine
email

Recent publications

Molecular determinants of sotorasib clinical efficacy in KRASG12C-mutated non-small-cell lung cancer
Nature Medicine 2025cited by 29position: middledoi
Datopotamab Deruxtecan Versus Docetaxel for Previously Treated Advanced or Metastatic Non–Small Cell Lung Cancer: The Randomized, Open-Label Phase III TROPION-Lung01 Study
Journal of Clinical Oncology 2024cited by 165position: middledoi
Sotorasib versus docetaxel for previously treated non-small-cell lung cancer with KRASG12C mutation: a randomised, open-label, phase 3 trial
The Lancet 2023cited by 547position: middledoi
Genomic characteristics and clinical significance of CD56+ circulating tumor cells in small cell lung cancer
Scientific Reports 2023cited by 4position: middledoi
Genomic characteristics and clinical significance of CD56+ Circulating Tumor Cells in Small Cell Lung Cancer
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 1position: middledoi
Consolidation nivolumab and ipilimumab versus observation in limited-disease small-cell lung cancer after chemo-radiotherapy – results from the randomised phase II ETOP/IFCT 4-12 STIMULI trial
Annals of Oncology 2021cited by 111position: middledoi
Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial
The Lancet 2019cited by 2,157position: middledoi
Clinical outcomes of non–small-cell lung cancer patients with BRAF mutations: results from the French Cooperative Thoracic Intergroup biomarkers France study
European Journal of Cancer 2019cited by 25position: middledoi
Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP28673 and NP28761) of Alectinib in ALK -positive Non-Small Cell Lung Cancer
Journal of Thoracic Oncology 2017cited by 82position: middledoi
Efficacy of alectinib in central nervous system metastases in crizotinib-resistant ALK -positive non–small-cell lung cancer: Comparison of RECIST 1.1 and RANO-HGG criteria
European Journal of Cancer 2017cited by 28position: middledoi
Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer
Annals of Oncology 2016cited by 161position: middledoi
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial
The Lancet Oncology 2015cited by 1,426position: middledoi
Phase II Study of Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in Patients with Advanced, Refractory Squamous Non-Small Cell Lung Cancer
International Journal of Radiation Oncology*Biology*Physics 2014cited by 19position: middledoi
Efficacy and Safety of Onartuzumab in Combination With First-Line Bevacizumab- or Pemetrexed-Based Chemotherapy Regimens in Advanced Nonsquamous Non-Small Cell Lung Cancer (nsNSCLC): Results From a Phase 2, Placebo-Controlled Study (GO27821)
International Journal of Radiation Oncology*Biology*Physics 2014cited by 3position: middledoi
Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial)
Annals of Oncology 2013cited by 56position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Fabrice Barlési · Guangdong Academy of Medical Sciences3 papers (2017–2019) · 2 papers (2022–2023) · 2 papers (2022–2023) · 2 papers (2022–2023)James Chih‐Hsin Yang · National Institutes of Health2 papers (2017–2017)Efstathios–Iason Vlachavas · German Cancer Research Center2 papers (2022–2023)Walter Bordogna · Roche (Switzerland)2 papers (2017–2017)Aristotelis Chatziioannou · Academy of Athens2 papers (2022–2023) · 2 papers (2022–2023) · 2 papers (2022–2023) · 2 papers (2022–2023) · 2 papers (2022–2023)Alice T. Shaw · Harvard University2 papers (2017–2017)Ali Zeaiter · PharmaMar (Spain)2 papers (2017–2017)Sai‐Hong Ignatius Ou · University of California, Irvine Medical Center2 papers (2017–2017)Dong-Wan Kim · Korea University2 papers (2017–2017)Leora Horn · Vanderbilt University Medical Center2 papers (2014–2016)Sophie Golding · University of Lausanne2 papers (2017–2017)Lucio Crinò · Ospedale Santa Maria2 papers (2017–2017) · 2 papers (2022–2023)