Area of research
Cardiology and Cardiovascular Medicine · Complementary and alternative medicine
Research interest
Research interests include Traditional Chinese Medicine Analysis, Lipid metabolism and disorders, Inflammasome and immune disorders, and Cardiac Fibrosis and Remodeling.
Quality and composition control of complex TCM preparations through a novel “Herbs-in vivo Compounds-Targets-Pathways” network methodology: The case of Lianhuaqingwen capsules
Targeting LKB1–AMPK–SIRT1–induced autophagy and mitophagy pathways improves cerebrovascular homeostasis in APP/PS1 mice
Bazi Bushen capsule modulates Akkermansia muciniphila and spermidine metabolism to attenuate brain aging in SAMP8 mice
Bazi Bushen capsule alleviates skin photoaging by targeting the KEAP1–NRF2 pathway
Lianhua Qingke Tablet in severe pneumonia: Clinical efficacy and immunoregulatory mechanisms
Tongxinluo alleviates myocardial ischemia–reperfusion injury by inhibiting the pyroptosis of endothelial cells via the NLRP3/Caspase-1/GSDMD signaling pathway
Pulmonary microvascular endothelial glycocalyx degradation as a key driver in COPD progression and its protection by Tongxinluo
Protective role of Tongxinluo in mitigating myocardial fibrosis in mice with acute myocardial infarction via neuregulin-1 upregulation and Inhibition of endothelium-interstitial transition
Hypoxia-conditioned cardiomyocyte-derived exosomes attenuate myocardial injury via ANP-mediated M2 macrophage polarization
Deciphering the molecular mechanisms of QLQX capsules in heart failure: A multi-omics perspective
Intervention of Bazi Bushen Capsule on Benign Prostatic Hyperplasia Concomitant with Erectile Dysfunction Induced by Testosterone Supplementation in Spontaneously Hypertensive Rats
Endothelial cells as early therapeutic targets in chronic obstructive pulmonary disease: Insights into Tongxinluo’s multiple protective mechanisms against cigarette smoke-induced lung injury
Unraveling the neuroprotective potential of scalp electroacupuncture in ischemic stroke: A key role for electrical stimulation
Tongxinluo Activates PI3K/AKT Signaling Pathway to Inhibit Endothelial Mesenchymal Transition and Attenuate Myocardial Fibrosis after Ischemia-Reperfusion in Mice
Bazi Bushen ameliorates age-related energy metabolism dysregulation by targeting the IL-17/TNF inflammatory pathway associated with SASP
Lianhua Qingke Preserves Mucociliary Clearance in Rat with Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Maintaining Ciliated Cells Proportion and Protecting Structural Integrity and Beat Function of Cilia
Bazi Bushen mitigates age-related muscular atrophy by alleviating cellular senescence of skeletal muscle
Therapeutic effects of Lianhua Qingke on COPD and influenza virus-induced exacerbation of COPD are associated with the inhibition of NF-κB signaling and NLRP3 inflammasome responses
Ameliorating lipopolysaccharide induced acute lung injury with Lianhua Qingke: focus on pulmonary endothelial barrier protection
Bazi Bushen capsule attenuates cardiac systolic injury via SIRT3/SOD2 pathway in high-fat diet-fed ovariectomized mice
Impairment of pulmonary microvascular endothelial cells: The ground for COPD?
Combined Bacterial Translocation and Cholestasis Aggravates Liver Injury by Activation Pyroptosis in Obstructive Jaundice
The effectiveness of vasodilators on chronic obstructive pulmonary disease: A systematic review and meta-analysis
Bazi Bushen mitigates epigenetic aging and extends healthspan in naturally aging mice
Sophoridine manifests as a leading compound for anti-arrhythmia with multiple ion-channel blocking effects
Therapeutic potential of Lianhua Qingke in airway mucus hypersecretion of acute exacerbation of chronic obstructive pulmonary disease
Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction
Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
Dual targets of lethal apoptosis and protective autophagy in liver cancer with periplocymarin elicit a limited therapeutic effect