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Philippe Giguère

University of North Carolina at Chapel Hill · US
Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, Protein Kinase Regulation and GTPase Signaling, and SARS-CoV-2 and COVID-19 Research.
h-index
25
citations
4,187
works
70
NIH funding
primary concept
email

Recent publications

Structure-based discovery of opioid analgesics with reduced side effects
Nature 2016cited by 941position: middledoi
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine
PLoS ONE 2016cited by 43position: middledoi
Design and Discovery of Functionally Selective Serotonin 2C (5-HT<sub>2C</sub>) Receptor Agonists
Journal of Medicinal Chemistry 2016cited by 35position: middledoi
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
Nature Structural & Molecular Biology 2015cited by 769position: middledoi
A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation
Molecular Cell 2015cited by 36position: middledoi
Optimization of 2-Phenylcyclopropylmethylamines as Selective Serotonin 2C Receptor Agonists and Their Evaluation as Potential Antipsychotic Agents
Journal of Medicinal Chemistry 2015cited by 35position: middledoi
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models
Journal of Medicinal Chemistry 2015cited by 28position: middledoi
Design and synthesis of (2-(5-chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a selective serotonin 2C agonist
Tetrahedron Letters 2015cited by 15position: middledoi
Molecular control of δ-opioid receptor signalling
Nature 2014cited by 503position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Bryan L. Roth · University of North Carolina at Chapel Hill8 papers (2014–2016)John D. McCorvy · Medical College of Wisconsin5 papers (2015–2016)Xi‐Ping Huang · South China Agricultural University5 papers (2014–2016)Alan P. Kozikowski · University of Illinois Chicago4 papers (2015–2016)Jianjun Cheng · University of Illinois Chicago4 papers (2015–2016) · 3 papers (2015–2016)William C. Wetsel · Duke University3 papers (2015–2016) · 2 papers (2015–2015)Hu Zhu · The University of Texas MD Anderson Cancer Center2 papers (2015–2016)Wei Lv · University of Illinois Chicago2 papers (2015–2015)Brian K. Shoichet · Quantitative BioSciences2 papers (2016–2016) · 2 papers (2015–2015)Maria F. Sassano · University of Kansas Medical Center2 papers (2015–2016) · 1 papers (2015–2015)William E. Fantegrossi · Virginia Commonwealth University1 papers (2016–2016)Aashish Manglik · Chan Zuckerberg Initiative (United States)1 papers (2016–2016)Dipendra K. Aryal · Houston Methodist1 papers (2016–2016)Yue Xiong · University of North Carolina at Chapel Hill1 papers (2015–2015)Grégory Scherrer · Palo Alto University1 papers (2016–2016)Bradley W. Gray · University of Arkansas for Medical Sciences1 papers (2016–2016)