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Madhuri Hegde

BVI (United States) · US
🔎 Find collaborators in Genetics · Molecular Biology →
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Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genomics and Rare Diseases, Muscle Physiology and Disorders, Genomic variations and chromosomal abnormalities, and Cancer Genomics and Diagnostics.
h-index
50
citations
41,319
works
292
NIH funding
primary concept
email

Recent publications

Diagnostic yield from prenatal exome sequencing for non‐immune hydrops fetalis: A systematic review and meta‐analysis
Clinical Genetics 2023cited by 25position: middledoi
DMD-Associated Dilated Cardiomyopathy: Genotypes, Phenotypes, and Phenocopies
Circulation Genomic and Precision Medicine 2023cited by 19position: middledoi
Genetic testing for inherited colorectal cancer and polyposis, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG)
Genetics in Medicine 2021cited by 73position: lastdoi
A single NGS‐based assay covering the entire genomic sequence of the <i>DMD</i> gene facilitates diagnostic and newborn screening confirmatory testing
Human Mutation 2021cited by 52position: lastdoi
RNA-seq in DMD urinary stem cells recognized muscle-related transcription signatures and addressed the identification of atypical mutations by whole-genome sequencing
Human Genetics and Genomics Advances 2021cited by 12position: middledoi
Clinical and Genomic Evaluation of 207 Genetic Myopathies in the Indian Subcontinent
Frontiers in Neurology 2020cited by 49position: lastdoi
The Latin American experience with a next generation sequencing genetic panel for recessive limb-girdle muscular weakness and Pompe disease
Orphanet Journal of Rare Diseases 2020cited by 43position: middledoi
Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome
Hepatology 2019cited by 83position: middledoi
Clinical utility of RNA sequencing to resolve unusual GNE myopathy with a novel promoter deletion
Muscle & Nerve 2019cited by 24position: lastdoi
ClinGen Variant Curation Expert Panel experiences and standardized processes for disease and gene‐level specification of the ACMG/AMP guidelines for sequence variant interpretation
Human Mutation 2018cited by 216position: middledoi
Genetic landscape and novel disease mechanisms from a large <scp>LGMD</scp> cohort of 4656 patients
Annals of Clinical and Translational Neurology 2018cited by 185position: lastdoi
Gene‐specific criteria for <i>PTEN</i> variant curation: Recommendations from the ClinGen PTEN Expert Panel
Human Mutation 2018cited by 171position: middledoi
Evidence-Based Consensus and Systematic Review on Reducing the Time to Diagnosis of Duchenne Muscular Dystrophy
The Journal of Pediatrics 2018cited by 44position: middledoi
Why West? Comparisons of clinical, genetic and molecular features of infants with and without spasms
PLoS ONE 2018cited by 35position: lastdoi
Inferring the effect of genomic variation in the new era of genomics
Human Mutation 2018cited by 29position: lastdoi
Diagnostic Yield From 339 Epilepsy Patients Screened on a Clinical Gene Panel
Pediatric Neurology 2017cited by 111position: middledoi
Development and Validation of Clinical Whole-Exome and Whole-Genome Sequencing for Detection of Germline Variants in Inherited Disease
Archives of Pathology & Laboratory Medicine 2017cited by 56position: firstdoi
Gene and Variant Annotation for Mendelian Disorders in the Era of Advanced Sequencing Technologies
Annual Review of Genomics and Human Genetics 2017cited by 47position: lastdoi
The Case for Laboratory Developed Procedures
Academic Pathology 2017cited by 26position: middledoi
Navigating highly homologous genes in a molecular diagnostic setting: a resource for clinical next-generation sequencing
Genetics in Medicine 2016cited by 247position: middledoi
Genomic Sequencing Procedure Microcosting Analysis and Health Economic Cost-Impact Analysis
Journal of Molecular Diagnostics 2016cited by 94position: middledoi
A survey of current practices for genomic sequencing test interpretation and reporting processes in US laboratories
Genetics in Medicine 2016cited by 86position: middledoi
Mutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia
The American Journal of Human Genetics 2016cited by 74position: middledoi
Reassessment of Genomic Sequence Variation to Harmonize Interpretation for Personalized Medicine
The American Journal of Human Genetics 2016cited by 54position: lastdoi
Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter
Science Signaling 2016cited by 54position: middledoi
De novo and inherited SCN8A epilepsy mutations detected by gene panel analysis
Epilepsy Research 2016cited by 41position: middledoi
Variants of uncertain significance in newborn screening disorders: implications for large-scale genomic sequencing
Genetics in Medicine 2016cited by 39position: middledoi
Gene Variant Databases and Sharing: Creating a Global Genomic Variant Database for Personalized Medicine
Human Mutation 2016cited by 29position: lastdoi
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
Genetics in Medicine 2015cited by 31,759position: middledoi
Good laboratory practice for clinical next-generation sequencing informatics pipelines
Nature Biotechnology 2015cited by 155position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Arunkanth Ankala · Emory University8 papers (2012–2018)Samya Chakravorty · Emory University7 papers (2017–2023)Lora Jh Bean · Centre for Omic Sciences6 papers (2013–2021)Babi Ramesh Reddy Nallamilli · Centre for Omic Sciences6 papers (2014–2021)Cristina da Silva · St George’s University Hospitals NHS Foundation Trust6 papers (2013–2018) · 5 papers (2013–2017)Birgit Funke · Children's Hospital of Philadelphia5 papers (2013–2018)Rong Mao · University of Utah5 papers (2013–2021)Alessandra Ferlini · University of Ferrara4 papers (2014–2021)C. Alexander Valencia · Plateforme de chimie biologique intégrative de Strasbourg4 papers (2012–2021)Ephrem Chin · Cambridge Reactor Design (United Kingdom)4 papers (2012–2023)Wayne W. Grody · University of California, Los Angeles4 papers (2012–2017)Heidi L. Rehm · Vanderbilt University Medical Center4 papers (2012–2018)Shruti Bhide · San Diego State University4 papers (2012–2013)Sharon E. Plon · Baylor College of Medicine4 papers (2012–2018)Karl V. Voelkerding · Walker (United States)3 papers (2014–2017)Carsten G. Bönnemann · National Institutes of Health3 papers (2012–2016)Elaine Lyon · West Coast University3 papers (2013–2017) · 3 papers (2012–2020) · 3 papers (2012–2020)
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