Area of research
Genetics · Immunology
Research interest
Research interests include Atherosclerosis and Cardiovascular Diseases, Single-cell and spatial transcriptomics, Diabetes and associated disorders, and Bacterial Genetics and Biotechnology.
Single-cell ‘omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveal heterogeneity of endothelial subtype and response to activating perturbations
TNFα increases the degradation of pyruvate dehydrogenase kinase 4 by the Lon protease to support proinflammatory genes
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning
Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits
Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics
The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner
Overexpression of the Cytokine BAFF and Autoimmunity Risk
Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells