Area of research
Computational Theory and Mathematics · Molecular Biology
Research interest
Research interests include Computational Drug Discovery Methods, Cancer Genomics and Diagnostics, Melanoma and MAPK Pathways, and CRISPR and Genetic Engineering.
Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy
Dedifferentiation maintains melanocyte stem cells in a dynamic niche
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
Loss of <i>TSC1/TSC2</i> sensitizes immune checkpoint blockade in non–small cell lung cancer
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer
Targeting <i>HER2</i> Exon 20 Insertion–Mutant Lung Adenocarcinoma with a Novel Tyrosine Kinase Inhibitor Mobocertinib
Targeting the Atf7ip–Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
Epigenetic CRISPR Screens Identify <i>Npm1</i> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer
The bone marrow microenvironment at single-cell resolution
<i>In Vivo</i> Epigenetic CRISPR Screen Identifies <i>Asf1a</i> as an Immunotherapeutic Target in <i>Kras</i> -Mutant Lung Adenocarcinoma
Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia
EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling
CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance
Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling