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Lai Guan Ng

Renji Hospital ·
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Area of research
Immunology
Research interest
Research interests include Immune cells in cancer, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, T-cell and B-cell Immunology, and Immune Response and Inflammation.
h-index
74
citations
36,418
works
197
NIH funding
primary concept
Biology
email

Recent publications

Matrix-producing neutrophils populate and shield the skin
Nature 2025cited by 58position: middledoi
From complexity to consensus: A roadmap for neutrophil classification
Immunity 2025cited by 25position: firstdoi
Septal LYVE1 <sup>+</sup> macrophages control adipocyte stem cell adipogenic potential
Science 2025cited by 20position: middledoi
Architecture of the neutrophil compartment
Nature 2025cited by 17position: middledoi
From NF-κB to cGAS: An interview with Prof. Zhijian James Chen on unraveling innate immunity
hLife 2025cited by 1position: middledoi
Deterministic reprogramming of neutrophils within tumors
Science 2024cited by 335position: lastdoi
Deciphering spatial domains from spatial multi-omics with SpatialGlue
Nature Methods 2024cited by 131position: middledoi
Timing and location dictate monocyte fate and their transition to tumor-associated macrophages
Science Immunology 2024cited by 46position: middledoi
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
Nature 2023cited by 195position: middledoi
Origin and Heterogeneity of Tissue Myeloid Cells: A Focus on GMP-Derived Monocytes and Neutrophils
Annual Review of Immunology 2023cited by 73position: firstdoi
Patients with COVID-19: in the dark-NETs of neutrophils
Cell Death and Differentiation 2021cited by 318position: middledoi
A subset of Kupffer cells regulates metabolism through the expression of CD36
Immunity 2021cited by 229position: middledoi
In Vivo Three‐Photon Imaging of Lipids using Ultrabright Fluorogens with Aggregation‐Induced Emission
Advanced Materials 2021cited by 111position: middledoi
MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche
Nature 2021cited by 100position: middledoi
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
Cell 2020cited by 917position: middledoi
A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart
Cell 2020cited by 718position: middledoi
Co-option of Neutrophil Fates by Tissue Environments
Cell 2020cited by 495position: middledoi
Deciphering human macrophage development at single-cell resolution
Nature 2020cited by 469position: middledoi
Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor
Immunity 2020cited by 264position: lastdoi
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19
Nature Communications 2020cited by 196position: middledoi
Efficient aortic lymphatic drainage is necessary for atherosclerosis regression induced by ezetimibe
Science Advances 2020cited by 52position: middledoi
Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Science 2019cited by 1,083position: middledoi
Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells
Cell 2019cited by 676position: middledoi
Polymerization-Enhanced Two-Photon Photosensitization for Precise Photodynamic Therapy
ACS Nano 2019cited by 237position: middledoi
NIR‐II‐Excited Intravital Two‐Photon Microscopy Distinguishes Deep Cerebral and Tumor Vasculatures with an Ultrabright NIR‐I AIE Luminogen
Advanced Materials 2019cited by 141position: middledoi
Granulopoiesis and Neutrophil Homeostasis: A Metabolic, Daily Balancing Act
Trends in Immunology 2019cited by 126position: lastdoi
Capturing the Fantastic Voyage of Monocytes Through Time and Space
Frontiers in Immunology 2019cited by 115position: middledoi
NIR‐II Excitable Conjugated Polymer Dots with Bright NIR‐I Emission for Deep In Vivo Two‐Photon Brain Imaging Through Intact Skull
Advanced Functional Materials 2019cited by 111position: middledoi
Dengue virus–elicited tryptase induces endothelial permeability and shock
Journal of Clinical Investigation 2019cited by 94position: middledoi
Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury
Nature Communications 2019cited by 80position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Bin Liu · Beijing Institute of Technology15 papers (2013–2021)Chi Ching Goh · National University of Singapore15 papers (2012–2019)Florent Ginhoux · Rockefeller University9 papers (2012–2023)Ben Zhong Tang · Chinese University of Hong Kong7 papers (2013–2018) · 6 papers (2013–2018)Shaowei Wang · National University of Singapore6 papers (2018–2021)Laurent Rénia · Hospital Universitario de Gran Canaria Doctor Negrín5 papers (2012–2020)Guangxue Feng · National University of Singapore5 papers (2013–2019)Immanuel Kwok · Nanyang Technological University4 papers (2019–2024)Véronique Angeli · National University of Singapore4 papers (2013–2020)J Li · Beijing Institute of Fashion Technology4 papers (2012–2015)Jie Liu · National University of Singapore4 papers (2013–2019)Junlong Geng · National University of Singapore4 papers (2013–2015)Benoît Malleret · National University of Singapore3 papers (2012–2015)Wolfgang Weninger · Centenary Institute3 papers (2012–2015)Rongrong Liu · Anhui Medical University3 papers (2013–2015)Jinmiao Chen · First Affiliated Hospital of Guangzhou Medical University3 papers (2015–2024)Shu Zhen Chong · National University of Singapore3 papers (2013–2019)Hwee Ying Lim · National University of Singapore3 papers (2013–2020)Peter See · Singapore Immunology Network3 papers (2012–2015)
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