Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, Genomics and Rare Diseases, and Hemoglobinopathies and Related Disorders.
Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk
Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood
Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation
N-Palmitoyl Glutamine Is a Candidate Mediator of Cardiorespiratory Fitness
Polygenic risk score for type 2 diabetes shows context-dependent effects across populations
EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints—A study in asthma
Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations
A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Clonal Hematopoiesis and Incident Heart Failure With Preserved Ejection Fraction
A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels
Demographic and Clinical Factors Associated With SARS-CoV-2 Spike 1 Antibody Response Among Vaccinated US Adults: the C4R Study
Rare variant contribution to the heritability of coronary artery disease
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes
A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances
EndoPRS: Incorporating Endophenotype Information to Improve Polygenic Risk Scores for Clinical Endpoints
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis
Trends in Prevalence of Gout Among US Asian Adults, 2011-2018
DNAmFitAge: biological age indicator incorporating physical fitness
Clonal Hematopoiesis of Indeterminate Potential (CHIP) and Incident Type 2 Diabetes Risk
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing
Canonical correlation analysis for multi-omics: Application to cross-cohort analysis
Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study
Association Between Whole Blood–Derived Mitochondrial DNA Copy Number, Low‐Density Lipoprotein Cholesterol, and Cardiovascular Disease Risk
Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing
Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas
The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes
Prediagnostic Glycoprotein Acetyl Levels and Incident and Recurrent Flare Risk Accounting for Serum Urate Levels: A <scp>Population‐Based</scp>, Prospective Study and Mendelian Randomization Analysis
Differences in the Circulating Proteome in Individuals with versus without Sickle Cell Trait