Area of research
Molecular Biology · Oncology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Epigenetics and DNA Methylation, Cancer Research and Treatments, and Immune cells in cancer.
Discovery of Divergent Oncostatin M Receptor-driven Pathways Across Fibrotic and Inflammatory Conditions
Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma
Proteomic characterization of acute kidney injury in patients hospitalized with SARS-CoV2 infection
Spatial Positioning and Matrix Programs of Cancer-Associated Fibroblasts Promote T-cell Exclusion in Human Lung Tumors
Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity
Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn’s Disease
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification
The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments
Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes
Intestinal Host Response to SARS-CoV-2 Infection and COVID-19 Outcomes in Patients With Gastrointestinal Symptoms
A myeloid–stromal niche and gp130 rescue in NOD2-driven Crohn’s disease
Immunology of COVID-19: Current State of the Science
A conserved dendritic-cell regulatory program limits antitumour immunity
DNA methylation disruption reshapes the hematopoietic differentiation landscape
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing
The mutation spectrum in genomic late replication domains shapes mammalian GC content
Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors