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Christine M. Bestvina

Duke University Hospital · US
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Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Lung Cancer Treatments and Mutations, Colorectal Cancer Treatments and Studies, Cancer Immunotherapy and Biomarkers, and Genetic factors in colorectal cancer.
h-index
20
citations
3,951
works
262
NIH funding
primary concept
Medicine
email

Recent publications

Immunotherapy in advanced, <i>KRAS</i> G12C-mutant non-small-cell lung cancer: current strategies and future directions
Therapeutic Advances in Medical Oncology 2025cited by 9position: lastdoi
Risk Factors for COVID-19–Related Hospitalization and Death in Patients With Cancer
JAMA Oncology 2025cited by 6position: middledoi
Abstract CT109: A first-in-human phase 1 study of LY4050784, an oral, potent, and selective SMARCA2 inhibitor, in patients with advanced solid tumors with <i>SMARCA4</i> alterations (Trial in Progress)
Cancer Research 2025cited by 3position: middledoi
Clinical strategies for lung cancer management: Recommendations from the Bridging the Gaps Lung Cancer Consensus Conference 2024
Cancer 2025cited by 2position: middledoi
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors
Nature 2024cited by 145position: middledoi
Sotorasib with panitumumab in chemotherapy-refractory KRASG12C-mutated colorectal cancer: a phase 1b trial
Nature Medicine 2024cited by 82position: middledoi
Evaluation of Major Pathologic Response and Pathologic Complete Response as Surrogate End Points for Survival in Randomized Controlled Trials of Neoadjuvant Immune Checkpoint Blockade in Resectable in NSCLC
Journal of Thoracic Oncology 2024cited by 70position: middledoi
Cost of genetic testing, delayed care, and suboptimal treatment associated with polymerase chain reaction versus next-generation sequencing biomarker testing for genomic alterations in metastatic non-small cell lung cancer
Journal of Medical Economics 2024cited by 13position: firstdoi
Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC
Cancer Discovery 2023cited by 178position: middledoi
Early-Stage Lung Cancer: Using Circulating Tumor DNA to Get Personal
Journal of Clinical Oncology 2023cited by 29position: firstdoi
The Role of MET in Resistance to EGFR Inhibition in NSCLC: A Review of Mechanisms and Treatment Implications
Cancers 2023cited by 28position: lastdoi
Brief Report: Discordance Between Liquid and Tissue Biopsy-Based Next-Generation Sequencing in Lung Adenocarcinoma at Disease Progression
Clinical Lung Cancer 2023cited by 16position: lastdoi
Abnormalities on baseline chest imaging are risk factors for immune checkpoint inhibitor associated pneumonitis
Respiratory Medicine 2023cited by 8position: middledoi
Highly aneuploid non-small cell lung cancer shows enhanced responsiveness to concurrent radiation and immune checkpoint blockade
Nature Cancer 2022cited by 89position: middledoi
Brief Report: Chylothorax and Chylous Ascites During RET Tyrosine Kinase Inhibitor Therapy
Journal of Thoracic Oncology 2022cited by 45position: middledoi
Predictors of Pneumonitis in Combined Thoracic Stereotactic Body Radiation Therapy and Immunotherapy
International Journal of Radiation Oncology*Biology*Physics 2022cited by 23position: middledoi
A Definitive Prognostication System for Patients With Thoracic Malignancies Diagnosed With Coronavirus Disease 2019: An Update From the TERAVOLT Registry
Journal of Thoracic Oncology 2022cited by 21position: middledoi
Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer therapies
Journal for ImmunoTherapy of Cancer 2022cited by 19position: middledoi
Meeting an un-MET need: Targeting MET in non-small cell lung cancer
Frontiers in Oncology 2022cited by 19position: lastdoi
Alliance A082002 -a randomized phase II/III trial of modern immunotherapy-based systemic therapy with or without SBRT for PD-L1-negative, advanced non-small cell lung cancer
Clinical Lung Cancer 2022cited by 18position: middledoi
Phase I study of anti-epidermal growth factor receptor antibody-drug conjugate serclutamab talirine: Safety, pharmacokinetics, and antitumor activity in advanced glioblastoma
Neuro-Oncology Advances 2022cited by 13position: middledoi
Severity of COVID-19 in patients with lung cancer: evidence and challenges
Journal for ImmunoTherapy of Cancer 2021cited by 155position: middledoi
A Phase 1 Trial of Concurrent or Sequential Ipilimumab, Nivolumab, and Stereotactic Body Radiotherapy in Patients With Stage IV NSCLC Study
Journal of Thoracic Oncology 2021cited by 139position: firstdoi
CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer
Scientific Reports 2021cited by 106position: middledoi
Neutrophil-to-Lymphocyte Ratio Is a Predictive Biomarker in Patients with Epidermal Growth Factor Receptor (EGFR) Mutated Advanced Non-Small Cell Lung Cancer (NSCLC) Treated with Tyrosine Kinase Inhibitor (TKI) Therapy
Cancers 2021cited by 28position: middledoi
Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
The Lancet 2020cited by 1,798position: middledoi
Association of STK11/LKB1 genomic alterations with lack of benefit from the addition of pembrolizumab to platinum doublet chemotherapy in non-squamous non-small cell lung cancer.
Journal of Clinical Oncology 2019cited by 101position: middledoi
Implementation of Advance Care Planning in Oncology: A Review of the Literature
Journal of Oncology Practice 2017cited by 100position: firstdoi
Chemotherapy for Endometrial Cancer in Adjuvant and Advanced Disease Settings
The Oncologist 2016cited by 119position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Everett E. Vokes · University of Illinois Chicago6 papers (2021–2024)Marina Chiara Garassino · Comprehensive Cardiovascular5 papers (2021–2025)Jyoti D. Patel · Northwestern University5 papers (2021–2023)Steven J. Chmura · University of Chicago Medical Center4 papers (2021–2022)Sherin J. Rouhani · Harvard University4 papers (2021–2023)Sean P. Pitroda · University of Chicago Medical Center4 papers (2021–2022)Ralph R. Weichselbaum · University of Chicago Medical Center3 papers (2021–2022)Philip C. Hoffman · University of Chicago3 papers (2021–2023)Aditya Juloori · University of Chicago3 papers (2021–2022)Kelli B. Pointer · Dartmouth College3 papers (2021–2022)Stanley I. Gutiontov · Aurora Health Care2 papers (2021–2022)Liam F. Spurr · Broad Institute2 papers (2021–2022)Gerald S. Falchook · Sarah Cannon Research Institute2 papers (2024–2025)Justin F. Gainor · Harvard University2 papers (2019–2022)Thomas F. Gajewski · University of Illinois Chicago2 papers (2022–2022)William Tyler Turchan · University of Chicago2 papers (2021–2022)Jeremy P. Segal · University of Chicago2 papers (2021–2023)Maximilian Diehn · Stanford University2 papers (2022–2023)John H. Strickler · Cancer Institute (WIA)2 papers (2022–2024)Septimiu Murgu · University of Chicago2 papers (2021–2022)
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