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Jacob Vorstman

Centre Hospitalier Universitaire Sainte-Justine · CA
Area of research
Genetics · Molecular Biology
Research interest
Research interests include Congenital heart defects research, Genomic variations and chromosomal abnormalities, Autism Spectrum Disorder Research, and Genetics and Neurodevelopmental Disorders.
h-index
54
citations
16,495
works
248
NIH funding
primary concept
Medicine
email

Recent publications

Updated clinical practice recommendations for managing children with 22q11.2 deletion syndrome
Genetics in Medicine 2023cited by 88position: middledoi
Genomic architecture of autism from comprehensive whole-genome sequence annotation
Cell 2022cited by 274position: middledoi
Genes To Mental Health (G2MH): A Framework to Map the Combined Effects of Rare and Common Variants on Dimensions of Cognition and Psychopathology
American Journal of Psychiatry 2022cited by 65position: middledoi
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Nature Genetics 2022cited by 55position: middledoi
A genetics-first approach to understanding autism and schizophrenia spectrum disorders: the 22q11.2 deletion syndrome
Molecular Psychiatry 2022cited by 48position: middledoi
Barriers to genetic testing in clinical psychiatry and ways to overcome them: from clinicians’ attitudes to sociocultural differences between patients across the globe
Translational Psychiatry 2022cited by 47position: middledoi
Clinical validity assessment of genes frequently tested on intellectual disability/autism sequencing panels
Genetics in Medicine 2022cited by 24position: middledoi
The Language Profile of Preschool Children With 22q11.2 Deletion Syndrome and the Relationship With Speech Intelligibility
American Journal of Speech-Language Pathology 2022cited by 17position: middledoi
A normative chart for cognitive development in a genetically selected population
Neuropsychopharmacology 2021cited by 24position: middledoi
Narrative comprehension and production abilities of children with 22q11.2 deletion syndrome
Research in Developmental Disabilities 2021cited by 12position: middledoi
Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome
Nature Medicine 2020cited by 148position: lastdoi
A framework for an evidence-based gene list relevant to autism spectrum disorder
Nature Reviews Genetics 2020cited by 147position: lastdoi
Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion
Molecular Psychiatry 2020cited by 135position: middledoi
The role of rare compound heterozygous events in autism spectrum disorder
Translational Psychiatry 2020cited by 6position: lastdoi
A large data resource of genomic copy number variation across neurodevelopmental disorders
npj Genomic Medicine 2019cited by 199position: middledoi
Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study
Molecular Psychiatry 2019cited by 77position: middledoi
Complete Sequence of the 22q11.2 Allele in 1,053 Subjects with 22q11.2 Deletion Syndrome Reveals Modifiers of Conotruncal Heart Defects
The American Journal of Human Genetics 2019cited by 74position: middledoi
Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size
Molecular Psychiatry 2018cited by 197position: middledoi
Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia
Molecular Psychiatry 2018cited by 77position: middledoi
Understanding the pediatric psychiatric phenotype of 22q11.2 deletion syndrome
American Journal of Medical Genetics Part A 2018cited by 72position: lastdoi
Variance of IQ is partially dependent on deletion type among 1,427 22q11.2 deletion syndrome subjects
American Journal of Medical Genetics Part A 2018cited by 52position: middledoi
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
Nature Neuroscience 2017cited by 933position: middledoi
Autism genetics: opportunities and challenges for clinical translation
Nature Reviews Genetics 2017cited by 495position: firstdoi
Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder
Journal of Clinical Investigation 2017cited by 122position: middledoi
PEMapper and PECaller provide a simplified approach to whole-genome sequencing
Proceedings of the National Academy of Sciences 2017cited by 31position: middledoi
Early interventions in risk groups for schizophrenia: what are we waiting for?
Schizophrenia 2016cited by 139position: lastdoi
Rare copy number variants and congenital heart defects in the 22q11.2 deletion syndrome
Human Genetics 2016cited by 57position: middledoi
22q11.2 deletion syndrome
Nature Reviews Disease Primers 2015cited by 2,230position: middledoi
Cognitive Decline Preceding the Onset of Psychosis in Patients With 22q11.2 Deletion Syndrome
JAMA Psychiatry 2015cited by 296position: firstdoi
Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome
The American Journal of Human Genetics 2015cited by 73position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Anne S. Bassett · University Health Network3 papers (2012–2022)Celso Arango · King's College London3 papers (2015–2018)Carrie E. Bearden · Orygen3 papers (2016–2022)Jeremy Parr · Centre for Human Genetics3 papers (2017–2020)Elemi Breetvelt · Utrecht University3 papers (2012–2018)Ania Fiksinski · Hospital for Sick Children2 papers (2018–2022)Stephen W. Scherer · Children's Hospital2 papers (2020–2022)Emma Everaert · Utrecht University2 papers (2021–2022)Sasja N. Duijff · Utrecht University2 papers (2013–2016)Louise Gallagher · Griffith College Cork2 papers (2020–2020)Ann Swillen · KU Leuven2 papers (2015–2022)Antonio M. Persico · Aims Community College2 papers (2013–2015)Jeffrey Glennon · Tulane University2 papers (2013–2015)Jan K. Buitelaar · Universitat de Barcelona2 papers (2013–2015)Tessel Boerma · Utrecht University2 papers (2021–2022)Frank Wijnen · Utrecht University2 papers (2021–2022)Raquel E. Gur · Children's Hospital of Philadelphia2 papers (2016–2022)Jurjen J. Luykx · University of Edinburgh2 papers (2020–2022)Richard Anney · Cardiff University2 papers (2017–2020)Thérèse van Amelsvoort · Amsterdam University of Applied Sciences2 papers (2016–2022)