Area of research
Oncology · Ophthalmology
Research interest
Research interests include Drug Transport and Resistance Mechanisms, Retinal Development and Disorders, Amino Acid Enzymes and Metabolism, and Retinal Diseases and Treatments.
Recent advances in 3D cell culture models in cancer drug development
Cortical Actin Depolymerisation in 3D Cell Culture Enhances Extracellular Vesicle Secretion and Therapeutic Effects
Erdafitinib promotes ferroptosis in human uveal melanoma by inducing ferritinophagy and lysosome biogenesis via modulating the FGFR1/mTORC1/TFEB signaling axis
Research hotspots and trends of mesenchymal stem cell-derived extracellular vesicles for drug delivery: a bibliometric and visualization analysis from 2013 to 2023
Recent advances and prospects for lipid-based nanoparticles as drug carriers in the treatment of human retinal diseases
Structure–Interaction Relationship of Polymyxins with Lung Surfactant
Procyanidin B2 and rutin in Ginkgo biloba extracts protect human retinal pigment epithelial (RPE) cells from oxidative stress by modulating Nrf2 and Erk1/2 signalling
The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions
Optimization of inhalable liposomal powder formulations and evaluation of their in vitro drug delivery behavior in Calu-3 human lung epithelial cells
Impaired Transport Activity of Human Organic Anion Transporters (OATs) and Organic Anion Transporting Polypeptides (OATPs) by Wnt Inhibitors
Human macular Müller cells rely more on serine biosynthesis to combat oxidative stress than those from the periphery
Simvastatin protects photoreceptors from oxidative stress induced by all‐<scp><i>trans</i></scp>‐retinal, through the up‐regulation of interphotoreceptor retinoid binding protein
Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage
Paeoniflorin attenuates atRAL-induced oxidative stress, mitochondrial dysfunction and endoplasmic reticulum stress in retinal pigment epithelial cells via triggering Ca2+/CaMKII-dependent activation of AMPK
A derivative of betulinic acid protects human Retinal Pigment Epithelial (RPE) cells from cobalt chloride-induced acute hypoxic stress
The inhibitory effects of eighteen front-line antibiotics on the substrate uptake mediated by human Organic anion/cation transporters, Organic anion transporting polypeptides and Oligopeptide transporters in in vitro models
Puerarin inhibits amyloid β-induced NLRP3 inflammasome activation in retinal pigment epithelial cells via suppressing ROS-dependent oxidative and endoplasmic reticulum stresses
Trafficking and other regulatory mechanisms for organic anion transporting polypeptides and organic anion transporters that modulate cellular drug and xenobiotic influx and that are dysregulated in disease
Amyloid β induces NLRP3 inflammasome activation in retinal pigment epithelial cells via NADPH oxidase‐ and mitochondria‐dependent ROS production
Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition
Chloroquine and Hydroxychloroquine Are Novel Inhibitors of Human Organic Anion Transporting Polypeptide 1A2
Human oligopeptide transporter 2 (PEPT2) mediates cellular uptake of polymyxins
Puerarin Protects Human Neuroblastoma SH‐SY5Y Cells against Glutamate‐Induced Oxidative Stress and Mitochondrial Dysfunction
Investigation of Gallic Acid Induced Anticancer Effect in Human Breast Carcinoma MCF‐7 Cells
Ziyuglycoside II induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells
Selective Inhibition of Human Solute Carrier Transporters by Multikinase Inhibitors
Protective Effect of Paeoniflorin on Aβ25–35-Induced SH-SY5Y Cell Injury by Preventing Mitochondrial Dysfunction
Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2
The Expression of ABC Efflux Pump, Rv1217c–Rv1218c, and Its Association with Multidrug Resistance of Mycobacterium tuberculosis in China
Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites