Deyu Fang

Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch

Informing immunotherapy with multi-omics driven machine learning

CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4

The secoiridoid glycoside Gentiopicroside is a USP22 inhibitor with potent antitumor immunotherapeutic activity

Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2

IL-17A mediates pyroptosis via the ERK pathway and contributes to steroid resistance in CRSwNP

SEL1L-HRD1 ER-associated degradation suppresses hepatocyte hyperproliferation and liver cancer

HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease

Interactions Between Glycogen Synthase Kinase-3β Gene Polymorphisms, Negative Life Events, and Susceptibility to Major Depressive Disorder in a Chinese Population

CRISPR screen in regulatory T cells reveals modulators of Foxp3

USP22 controls iNKT immunity through MED1 suppression of histone H2A monoubiquitination

Association between type D personality and in-stent restenosis in patients treated with percutaneous coronary intervention: A mediation analysis of dietary patterns

CD73 expression on effector T cells sustained by TGF-β facilitates tumor resistance to anti-4-1BB/CD137 therapy

Spermidine Confers Liver Protection by Enhancing NRF2 Signaling Through a MAP1S‐Mediated Noncanonical Mechanism

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes

The endoplasmic reticulum–resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice

The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation

The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

Mismatch negativity as a potential neurobiological marker of early-stage Alzheimer disease and vascular dementia

GNB3 and CREB1 gene polymorphisms combined with negative life events increase susceptibility to major depression in a Chinese Han population

Interactions between the vascular endothelial growth factor gene polymorphism and life events in susceptibility to major depressive disorder in a Chinese population

Development and characterization of naive single-type tumor antigen-specific CD8⁺ T lymphocytes from murine pluripotent stem cells

Polymorphisms in 5-HTR1A and coupled G-proteins in association with negative life events increase susceptibility to suicide attempt

TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

Ubiquitin-specific peptidase 22 functions and its involvement in disease

The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity

Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas

IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation

Deleted in Breast Cancer 1 Suppresses B Cell Activation through RelB and Is Regulated by IKKα Phosphorylation

DBC1 Is a Suppressor of B Cell Activation by Negatively Regulating Alternative NF-κB Transcriptional Activity