Area of research
Molecular Biology · Oncology
Research interest
Research interests include RNA modifications and cancer, Cancer Cells and Metastasis, Cancer-related gene regulation, and Epigenetics and DNA Methylation.
CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1–CXCR2 induced NETs
CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer
Metabolic reprogramming driven by METTL1-mediated tRNA m7G modification promotes acquired anlotinib resistance in oral squamous cell carcinoma
ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration
Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification
Metabolic rewiring during bone development underlies tRNA m7G–associated primordial dwarfism
RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac4C modification
The tRNA methyltransferase Mettl1 governs ketogenesis through translational regulation and drives metabolic reprogramming in cardiomyocyte maturation
The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma
RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac <sup>4</sup> C modification
Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression
BET inhibition triggers antitumor immunity by enhancing MHC class I expression in head and neck squamous cell carcinoma
Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells
Tumor microenvironment in head and neck squamous cell carcinoma: Functions and regulatory mechanisms
FOSL1 promotes metastasis of head and neck squamous cell carcinoma through super-enhancer-driven transcription program
Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway
Deficiency of Mettl3 in Bladder Cancer Stem Cells Inhibits Bladder Cancer Progression and Angiogenesis
Sox9+ cells are required for salivary gland regeneration after radiation damage via the Wnt/β-catenin pathway
METTL3 Promotes Tumorigenesis and Metastasis through BMI1 m6A Methylation in Oral Squamous Cell Carcinoma
Mettl5 mediated 18S rRNA N6-methyladenosine (m6A) modification controls stem cell fate determination and neural function
METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma
Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis
Multifunctional Branched Nanostraw-Electroporation Platform for Intracellular Regulation and Monitoring of Circulating Tumor Cells
Targeting cancer stem cells in squamous cell carcinoma
Amelioration of Ductular Reaction by Stem Cell Derived Extracellular Vesicles in MDR2 Knockout Mice via Lethal‐7 microRNA
Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma
Long non-coding RNA HoxA-AS3 interacts with EZH2 to regulate lineage commitment of mesenchymal stem cells
Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model
Ubiquitin specific peptidase 21 regulates interleukin-8 expression, stem-cell like property of human renal cell carcinoma