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Joshua D. Webster

Gene Therapy Laboratory ·
Area of research
Molecular Biology · Oncology
Research interest
Research interests include Cell death mechanisms and regulation, Cancer Cells and Metastasis, Veterinary Oncology Research, and RNA modifications and cancer.
h-index
47
citations
10,148
works
170
NIH funding
primary concept
Medicine
email

Recent publications

RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury.
2025cited by 5position: contributordoi
cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A
Cell Death and Differentiation 2025cited by 2position: middledoi
Reviewer-in-training: A mentoring opportunity in the peer review process.
2025cited by 0position: contributordoi
cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A.
2025cited by 0position: contributordoi
Reporting guidelines for manuscripts that use artificial intelligence-based automated image analysis in <i>Veterinary Pathology</i>.
2025cited by 0position: contributordoi
Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
Nature 2025cited by 0position: middledoi
Author Correction: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis
Nature 2025cited by 0position: middledoi
Author Correction: Activity of caspase-8 determines plasticity between cell death pathways
Nature 2025cited by 0position: middledoi
ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1
Cell Death and Differentiation 2024cited by 31position: lastdoi
Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade
Nature Communications 2024cited by 28position: middledoi
ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1.
2024cited by 25position: contributordoi
N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
Immunity 2024cited by 24position: middledoi
Caspase cleavage of RIPK3 after Asp333 is dispensable for mouse embryogenesis
Cell Death and Differentiation 2024cited by 15position: middledoi
RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury
Cell Death and Differentiation 2024cited by 12position: middledoi
Caspase cleavage of RIPK3 after Asp<sup>333</sup> is dispensable for mouse embryogenesis.
2024cited by 11position: contributordoi
Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease.
2024cited by 1position: contributordoi
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
Nature 2023cited by 163position: middledoi
Targeted alveolar regeneration with Frizzled-specific agonists
Cell 2023cited by 80position: middledoi
Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects
Science Translational Medicine 2023cited by 18position: middledoi
Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
2023cited by 13position: contributordoi
T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction
EMBO Reports 2023cited by 13position: middledoi
T cell-dependent bispecific antibodies alter organ-specific endothelial cell-T cell interaction.
2023cited by 11position: contributordoi
XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death
Cell Death and Disease 2023cited by 9position: middledoi
XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death.
2023cited by 6position: contributordoi
Standardized Processing for Formalin-Fixed, Paraffin-Embedded Cell Pellet Immunohistochemistry Controls
Journal of Visualized Experiments 2022cited by 3position: lastdoi
Inhibition of the Receptor Interactive Protein Kinase 1 (RIP1) Pathway Prevents Acute Gvhd
Blood 2022cited by 1position: middledoi
NINJ1 mediates plasma membrane rupture during lytic cell death
Nature 2021cited by 789position: middledoi
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection
Cell Host & Microbe 2021cited by 182position: middledoi
Validating Immunohistochemistry Assay Specificity in Investigative Studies: Considerations for a Weight of Evidence Approach.
2021cited by 18position: contributordoi
Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury
Cell Death and Disease 2021cited by 16position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Kim Newton · Genentech26 papers (2015–2025)Vishva M. Dixit · Genentech17 papers (2015–2025) · 14 papers (2015–2025) · 11 papers (2018–2025)Rohit Reja · Gene Therapy Laboratory11 papers (2019–2025) · 11 papers (2021–2025)Merone Roose‐Girma · Genmab (United States)11 papers (2018–2025)Domagoj Vucic · Gene Therapy Laboratory10 papers (2018–2024)Zora Modrušan · Genetic Technologies (Australia)10 papers (2015–2025)Katherine E. Wickliffe · University of California, Berkeley8 papers (2018–2025)Tatiana Goncharov · Gene Therapy Laboratory6 papers (2019–2024)Donald S. Kirkpatrick · Altair Engineering (United States)6 papers (2016–2021)Wyne P. Lee · ATUM (United States)5 papers (2018–2020) · 5 papers (2018–2025) · 4 papers (2019–2025)Erik Verschueren · Gladstone Institutes4 papers (2018–2021)Keith R. Anderson · University of Colorado Denver3 papers (2019–2021) · 3 papers (2015–2019) · 3 papers (2019–2021)Sarah Kummerfeld · Garvan Institute of Medical Research3 papers (2015–2019)