Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research interests include Chemistry, G protein-coupled receptor, Receptor, Tachykinin receptor 1, Cell biology, and TRPV4.
Selective G protein signaling driven by substance P–neurokinin receptor dynamics
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes
Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice
Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists
The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability
Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization