Area of research
Immunology · Immunology and Allergy
Research interest
Research interests include Immune cells in cancer, Cell Adhesion Molecules Research, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, and Cancer Cells and Metastasis.
Functional Precision Medicine Using MicroOrganoSpheres for Treatment Response Prediction in Advanced Colorectal Cancer
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance
Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability
Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes
TROPHIT1—a randomized, open-label, multicenter, phase II/III trial of sacituzumab govitecan compared to standard of care in metastatic colorectal cancer patients
Dark force rising: Reawakening and targeting of fetal-like stem cells in colorectal cancer
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
Lymphotoxin beta‐activated <scp>LTBR/NIK/RELB</scp> axis drives proliferation in cholangiocarcinoma
Casein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging
Abstract 2929: Multiplexed somatic genome editing to model and investigate advanced colorectal cancer
Automated Lesion Detection in Endoscopic Imagery for Small Animal Models
Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression
Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing
Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC
From organoids to bedside: Advances in modeling, decoding and targeting of colorectal cancer
Modeling Colorectal Cancer Progression Reveals Niche-Dependent Clonal Selection
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features
26P NOTCH1 driven metastasis in BRAF mutated colorectal cancer
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
Advances in colon cancer research: in vitro and animal models
LRG1 destabilizes tumor vessels and restricts immunotherapeutic potency
BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer
Stromal WNTer Keeps the Tumor Cold and Drives Metastasis
Genome-Wide Analysis of c-MYC-Regulated mRNAs and miRNAs and c-MYC DNA-Binding by Next-Generation Sequencing
Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
Colorectal Cancers Mimic Structural Organization of Normal Colonic Crypts
AP4 is required for mitogen- and c-MYC-induced cell cycle progression
SNAIL and miR‐34a feed‐forward regulation of ZNF281/ZBP99 promotes epithelial–mesenchymal transition