Area of research
Molecular Biology · Nephrology
Research interest
Research interests include Chronic Kidney Disease and Diabetes, Genetic Associations and Epidemiology, Metabolomics and Mass Spectrometry Studies, and Epigenetics and DNA Methylation.
Accelerated multi-organ proteomic aging is detectable decades before dementia onset
Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma
Coupling metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and human traits
Epigenetic markers of disease risk and psychotherapy response in anxiety disorders – a longitudinal analysis of the DNA methylome
Biological organ ages associate with risk of chronic diseases in a community-based population
Sex Differences in Hypertension and Its Management Throughout Life
Association of Integrated Proteomic and Metabolomic Modules with Risk of Kidney Disease Progression
Plasma proteomics of acute tubular injury
Associations of Urine and Plasma Metabolites With Kidney Failure and Death in a Chronic Kidney Disease Cohort
Serum and Urine Metabolites and Kidney Function
metaGWASmanager: a toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia
metaGWASmanager: A toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia
Multiancestry Genome-Wide Association Meta-Analyses of Kidney Function Traits: The CKDGen Consortium R5 Project
Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life
Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine
Proteomic Predictors of Incident Diabetes: Results From the Atherosclerosis Risk in Communities (ARIC) Study
Proteomics: Progress and Promise of High-Throughput Proteomics in Chronic Kidney Disease
Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage
In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts
Coupling of metabolomics and exome sequencing reveals graded effects of rare damaging heterozygous variants on gene function and resulting traits and diseases
Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases
Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension
Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases
Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study
MO048: Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
Meta-analyses identify DNA methylation associated with kidney function and damage
Proteins Associated with Risk of Kidney Function Decline in the General Population
Plasma Proteomics of Renal Function: A Transethnic Meta-Analysis and Mendelian Randomization Study