Area of research
Genetics · Reproductive Medicine
Research interest
Research interests include Biology, Zebrafish, Cell biology, Wnt signaling pathway, Transgene, and Mucopolysaccharidosis type II.
Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry
“Janus” efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
The pathogenesis of lysosomal storage disorders: beyond the engorgement of lysosomes to abnormal development and neuroinflammation
FGF signaling deregulation is associated with early developmental skeletal defects in animal models for mucopolysaccharidosis type II (MPSII)
Perturbations in cell signaling elicit early cardiac defects in mucopolysaccharidosis type II
Wnt/β-Catenin Signaling Defines Organizing Centers that Orchestrate Growth and Differentiation of the Regenerating Zebrafish Caudal Fin
Intracardiac flow dynamics regulate atrioventricular valve morphogenesis
A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development
Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling
Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer
A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish
Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization
Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling
Wnt activation promotes neuronal differentiation of Glioblastoma
RAB8B Is Required for Activity and Caveolar Endocytosis of LRP6
Generation and application of signaling pathway reporter lines in zebrafish
Emilin3 is required for notochord sheath integrity and interacts with Scube2 to regulate notochord-derived Hedgehog signals
In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains
Wnt Signaling Regulates Postembryonic Hypothalamic Progenitor Differentiation
Diverse Chemical Scaffolds Support Direct Inhibition of the Membrane-bound O-Acyltransferase Porcupine
Using transgenic reporters to visualize bone and cartilage signaling during development in vivo