Area of research
Molecular Biology · Physiology
Research interest
Research interests include Glycosylation and Glycoproteins Research, Sphingolipid Metabolism and Signaling, Lysosomal Storage Disorders Research, and Cancer, Hypoxia, and Metabolism.
Wnt-associated DKK3 in keratinocytes mediates radiation-induced hyperplasia, dermatitis and skin fibrosis
The SGLT2 Inhibitor Dapagliflozin Disrupts the Cell Cycle at High Concentrations Without Altering Glycosphingolipid (De Novo)Biosynthesis
Glucosylceramide Synthase Inhibition in Combination with Aripiprazole Sensitizes Hepatocellular Cancer Cells to Sorafenib and Doxorubicin
GD2 Expression in Medulloblastoma and Neuroblastoma for Personalized Immunotherapy: A Matter of Subtype
DKK3 Promotes Oxidative Stress‒Induced Fibroblast Activity
A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis
Glycolipid-dependent and lectin-driven transcytosis in mouse enterocytes
Blockade of Glycosphingolipid Synthesis Inhibits Cell Cycle and Spheroid Growth of Colon Cancer Cells In Vitro and Experimental Colon Cancer Incidence In Vivo
The prognostic value of galactosylceramide-sulfotransferase (Gal3ST1) in human renal cell carcinoma
Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis
Gangliosides modulate insulin secretion by pancreatic beta cells under glucose stress
Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner
Renal globotriaosylceramide facilitates tubular albumin absorption and its inhibition protects against acute kidney injury
Ganglioside deficiency in hypothalamic POMC neurons promotes body weight gain
Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals
Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis
Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells
Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors
Zeb1 affects epithelial cell adhesion by diverting glycosphingolipid metabolism
Direct acute tubular damage contributes to Shigatoxin‐mediated kidney failure
Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods
Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction
Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease.
1-O-acylceramides are natural components of human and mouse epidermis
Cell-specific in vivo functions of glycosphingolipids: Lessons from genetic deletions of enzymes involved in glycosphingolipid synthesis
Sulfatides are required for renal adaptation to chronic metabolic acidosis
Neuronal Expression of Glucosylceramide Synthase in Central Nervous System Regulates Body Weight and Energy Homeostasis
Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing
Glycosphingolipids Are Essential for Intestinal Endocytic Function
Globosides but Not Isoglobosides Can Impact the Development of Invariant NKT Cells and Their Interaction with Dendritic Cells