Area of research
Materials Chemistry · Molecular Biology
Research interest
Research interests include Chemistry, Topoisomerase, Biological activity, Chemical synthesis, Stereochemistry, and DNA gyrase.
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms
Synthetic macrolides overcoming MLSBK-resistant pathogens
Identification, Synthesis, and Biological Evaluation of Metabolites of the Experimental Cancer Treatment Drugs Indotecan (LMP400) and Indimitecan (LMP776) and Investigation of Isomerically Hydroxylated Indenoisoquinoline Analogues as Topoisomerase I Poisons