Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Biology, Cell biology, Cell growth, DNA replication, Methionine, and Metabolism.
A non-syndromic orofacial cleft risk locus links tRNA splicing defects to neural crest cell pathologies
Sideroflexins enable mitochondrial transport of polar neutral amino acids
A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
Cancer tissue of origin constrains the growth and metabolism of metastases
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids
Nucleotide imbalance decouples cell growth from cell proliferation
Methionine synthase is essential for cancer cell proliferation in physiological folate environments
Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma
Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells