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Jeroen R. Huyghe

Fred Hutch Cancer Center ·
Area of research
Genetics · Oncology
Research interest
Research interests include Genetic Associations and Epidemiology, Genetic factors in colorectal cancer, Colorectal Cancer Screening and Detection, and Cancer Immunotherapy and Biomarkers.
h-index
45
citations
9,168
works
350
NIH funding
primary concept
Medicine
email

Recent publications

TGF-β Pathway–Based Polygenic Risk Score Modifies the Association between Red Meat Intake and Colorectal Cancer Risk: Application of a Novel Pathway-Based PRS Method
Cancer Epidemiology Biomarkers & Prevention 2026cited by 1position: middledoi
ROSIE: AI generation of multiplex immunofluorescence staining from histopathology images
Nature Communications 2025cited by 19position: middledoi
Using gene-environment interactions to explore pathways for colorectal cancer risk
EBioMedicine 2025cited by 2position: middledoi
Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study
JNCI Cancer Spectrum 2025cited by 1position: middledoi
Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies
Cancer Epidemiology Biomarkers & Prevention 2025cited by 1position: middledoi
Genetic risk factors modulate the association between physical activity and colorectal cancer
Research Square 2025cited by 1position: middledoi
Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer
Annals of Oncology 2024cited by 67position: middledoi
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes
Nature Communications 2024cited by 18position: middledoi
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer
EBioMedicine 2024cited by 12position: middledoi
Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
British Journal of Cancer 2024cited by 10position: middledoi
Body size and risk of colorectal cancer molecular defined subtypes and pathways: Mendelian randomization analyses
EBioMedicine 2024cited by 9position: middledoi
Two genome-wide interaction loci modify the association of nonsteroidal anti-inflammatory drugs with colorectal cancer
Science Advances 2024cited by 6position: middledoi
Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature
Cancer Epidemiology Biomarkers & Prevention 2024cited by 3position: middledoi
Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing
American Journal of Clinical Nutrition 2024cited by 3position: middledoi
Characterization of Additive Gene–environment Interactions For Colorectal Cancer Risk
Epidemiology 2024cited by 3position: middledoi
Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer
medRxiv 2024cited by 0position: middledoi
Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study
International Journal of Cancer 2023cited by 60position: middledoi
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations
Nature Communications 2023cited by 27position: middledoi
Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival
medRxiv 2023cited by 22position: middledoi
Genome-Wide Gene–Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk
Cancer Epidemiology Biomarkers & Prevention 2023cited by 15position: middledoi
A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk
Cancer Research 2023cited by 14position: middledoi
Probing the diabetes and colorectal cancer relationship using gene – environment interaction analyses
British Journal of Cancer 2023cited by 14position: middledoi
Novel insights into genetic susceptibility for colorectal cancer from transcriptome-wide association and functional investigation
JNCI Journal of the National Cancer Institute 2023cited by 12position: middledoi
Genome-wide interaction analysis of folate for colorectal cancer risk
American Journal of Clinical Nutrition 2023cited by 11position: middledoi
Identifying metabolic features of colorectal cancer liability using Mendelian randomization
eLife 2023cited by 8position: middledoi
Elucidating the Risk of Colorectal Cancer for Variants in Hereditary Colorectal Cancer Genes
Gastroenterology 2023cited by 6position: middledoi
Validation of a Genetic-Enhanced Risk Prediction Model for Colorectal Cancer in a Large Community-Based Cohort
Cancer Epidemiology Biomarkers & Prevention 2023cited by 6position: middledoi
Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Nature Genetics 2023cited by 4position: middledoi
Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomization study
medRxiv 2023cited by 2position: middledoi
Identifying metabolic features of colorectal cancer liability using Mendelian randomization
eLife 2023cited by 1position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Rish K. Pai · Sinai Health System5 papers (2021–2023)Caroline J. Bull · University of Bristol4 papers (2023–2023)Neil Murphy · World Health Organization - Lyon Office4 papers (2023–2023)Kimberley Burrows · Charité - Universitätsmedizin Berlin4 papers (2023–2023)Marc J. Gunter · World Health Organization - Lyon Office4 papers (2023–2023)Hermann Brenner · Stanford University4 papers (2023–2023)Emma E. Vincent · McGill University Health Centre4 papers (2023–2023)Andrei‐Emil Constantinescu · University of Bristol4 papers (2023–2023)Loı̈c Le Marchand · The London College3 papers (2021–2023)Daniel D. Buchanan · Morehouse College3 papers (2021–2023)Mark A. Jenkins · Georgia Southern University3 papers (2021–2023)Jane C. Figueiredo · University of Southern California3 papers (2021–2023)Vı́ctor Moreno · Hospital Universitario de Móstoles2 papers (2023–2023)Maria Carolina Borges · University of Bristol2 papers (2023–2023)Ruth E. Mitchell · University of Bristol2 papers (2023–2023)Ulrike Peters · Fred Hutch Cancer Center2 papers (2021–2025)Nicholas Jones · The Ohio State University Wexner Medical Center2 papers (2023–2023)Andrew T. Chan · Monash Institute of Medical Research2 papers (2023–2023)Iona Cheng · University of California, San Francisco2 papers (2023–2023)Mauro D’Amato · Ikerbasque2 papers (2023–2023)