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Jason P. Appleton

University of Birmingham · GB
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Area of research
Epidemiology · Neurology
Research interest
Research interests include Medicine, Stroke (engine), Modified Rankin Scale, Randomized controlled trial, Aspirin, and Tranexamic acid.
h-index
citations
1,263
works
17
NIH funding
primary concept
email

Recent publications

Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack
Stroke Vascular and Interventional Neurology 2023cited by 45position: middledoi
Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): effects on outcomes at day 365 in a randomised, sham-controlled, blinded, phase III, superiority ambulance-based trial
BMJ Neurology Open 2023cited by 2position: middledoi
Effects of blood pressure and tranexamic acid in spontaneous intracerebral haemorrhage: a secondary analysis of a large randomised controlled trial
BMJ Neurology Open 2023cited by 2position: firstdoi
Perfusion Imaging for Endovascular Thrombectomy in Acute Ischemic Stroke Is Associated With Improved Functional Outcomes in the Early and Late Time Windows
Stroke 2022cited by 60position: middledoi
Effect of continuing versus stopping pre-stroke antihypertensive agents within 12 h on outcome after stroke: A subgroup analysis of the efficacy of nitric oxide in stroke (ENOS) trial
EClinicalMedicine 2022cited by 7position: middledoi
Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data
The Lancet 2020cited by 179position: middledoi
Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial
The Lancet 2019cited by 194position: middledoi
Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT
Health Technology Assessment 2019cited by 28position: middledoi
Associations between change in blood pressure and functional outcome, early events and death
Journal of Hypertension 2019cited by 4position: middledoi
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
The Lancet 2018cited by 475position: middledoi
Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT
Health Technology Assessment 2018cited by 15position: middledoi
Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’
European Stroke Journal 2018cited by 11position: middledoi
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial
The Lancet 2017cited by 179position: middledoi
Assessment of consent models as an ethical consideration in the conduct of prehospital ambulance randomised controlled clinical trials: a systematic review
BMC Medical Research Methodology 2017cited by 29position: middledoi
Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)
International Journal of Stroke 2017cited by 26position: firstdoi
PP15 Consent as an ethical consideration in the conduct of prehospital ambulance randomised controlled clinical trials: a systematic review
Emergency Medicine Journal 2017cited by 0position: middledoi
Baseline characteristics of the 3096 patients recruited into the ‘Triple Antiplatelets for Reducing Dependency after Ischemic Stroke’ trial
International Journal of Stroke 2016cited by 7position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Philip M. Bath · Nottingham University Hospitals NHS Trust11 papers (2016–2023)Nikola Sprigg · Nottingham University Hospitals NHS Trust9 papers (2016–2023)Lisa J Woodhouse · University of Edinburgh8 papers (2016–2023)Polly Scutt · London School of Hygiene & Tropical Medicine6 papers (2016–2023)Kailash Krishnan · University of Edinburgh6 papers (2016–2023)Timothy J. England · University of Nottingham6 papers (2016–2023)Thompson Robinson · University of Leicester5 papers (2016–2023)Stuart Pocock · London School of Hygiene & Tropical Medicine5 papers (2016–2023)Joanna M. Wardlaw · Universitätsmedizin Greifswald4 papers (2017–2023)Mark Dixon · University of Nottingham4 papers (2017–2018)Hanne Christensen · University of Copenhagen4 papers (2016–2023)A Niroshan Siriwardena · Swansea University3 papers (2017–2023) · 3 papers (2016–2023)Robert A. Dineen · University of Nottingham3 papers (2016–2023)Zhe Kang Law · University of Edinburgh2 papers (2023–2023)Annemarei Ranta · Utrecht University2 papers (2016–2018)John Gommans · University of Edinburgh2 papers (2019–2022)Hugh S. Markus · Oxford Research Group2 papers (2016–2018)Stephen Phillips · Dalhousie University2 papers (2019–2022)Stephanie Armstrong · Medical College of Wisconsin2 papers (2017–2017)
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