Area of research
Molecular Biology · Computational Theory and Mathematics
Research interest
Research interests include Computational Drug Discovery Methods, Cytokine Signaling Pathways and Interactions, Heat shock proteins research, and Monoclonal and Polyclonal Antibodies Research.
Structural basis of Janus kinase trans-activation
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis
Structural insight into guanylyl cyclase receptor hijacking of the kinase–Hsp90 regulatory mechanism
Structural insight into guanylyl cyclase receptor hijacking of the kinase–Hsp90 regulatory mechanism
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation
Organizing structural principles of the IL-17 ligand–receptor axis
Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Viral G Protein–Coupled Receptors Encoded by β- and γ-Herpesviruses
Structure of the IL-27 quaternary receptor signaling complex
Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10
Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling
Structure and selectivity engineering of the M <sub>1</sub> muscarinic receptor toxin complex
Structure of the IFNγ receptor complex guides design of biased agonists
Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy