Area of research
Atmospheric Science · Molecular Biology
Research interest
Research interests include Atmospheric chemistry and aerosols, Enzyme Catalysis and Immobilization, Atmospheric Ozone and Climate, and Microbial Metabolic Engineering and Bioproduction.
Biocatalytic, enantioenriched primary amination of tertiary C–H bonds
Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism
MicroED Structure of a Protoglobin Reactive Carbene Intermediate
In vivo hypermutation and continuous evolution
Biocatalytic Carbene Transfer Using Diazirines
In vivo hypermutation and continuous evolution
Protoglobin‐Catalyzed Formation of <i>cis</i>‐Trifluoromethyl‐Substituted Cyclopropanes by Carbene Transfer
An Enzymatic Platform for Primary Amination of 1-Aryl-2-alkyl Alkynes
Origin and Control of Chemoselectivity in Cytochrome <i>c</i> Catalyzed Carbene Transfer into Si–H and N–H bonds
Selective Enzymatic Oxidation of Silanes to Silanols
A Biocatalytic Platform for Synthesis of Chiral <i>α-</i> Trifluoromethylated Organoborons
Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation
Catalytic iron-carbene intermediate revealed in a cytochrome <i>c</i> carbene transferase
Genetically Encoded Spy Peptide Fusion System to Detect Plasma Membrane-Localized Proteins In Vivo
Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry
Isobutanol production at elevated temperatures in thermophilic Geobacillus thermoglucosidasius
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
Enantioselective Intramolecular CH Amination Catalyzed by Engineered Cytochrome P450 Enzymes In Vitro and In Vivo
Comparison of random mutagenesis and semi-rational designed libraries for improved cytochrome P450 BM3-catalyzed hydroxylation of small alkanes
Aerosol observations and growth rates downwind of the anvil of a deep tropical thunderstorm
Aerosol observations and growth rates in the tropical tropopause layer
Evolving Hemoproteins for New-to-Nature Ring-Forming Reactions
Next-Generation Protein Engineering: Machine Learning for Enzyme Engineering
Expanding the Enzyme Repertoire by Evolution and Engineering
SusChEM: Engineering and Evolution of Cytochrome P450 Enzymes for Non-Natural Chemistry
Collaborative Research: Metabolically Engineered Organisms for Conversion of Cellulose to Isobutanol
BIC: Collaborative Research: Evolutionary Optimization of Biological Circuits: Towards Cellular Programming
Laboratory Evolution of Biocatalysts for Methane Hydroxylation and Alkene Epoxidation
Qubic: Biological Information Technology Systems: Self-Perfecting Genetic Circuits
ME: Interagency Announcement of Opportunities in Metabolic Engineering: Laboratory Evolution of Carotenoid Biosynthetic Pathways
Tools for Directed Evolution of Oxygenases: High Throughput Screening of Epoxidation and Hydroxylation Catalysts
A Microfabricated Cell Sorter for Molecular Evolution
Selective Templated Polymers for Bioseparations
Selective Polymers For Protein Separations: Investigation of Novel Template Polymerization Techniques
Presidential Young Investigators Award
Engineering Protein Separations on Immobilized Metals