Ernest Fraenkel

An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration

TDP-43 loss induces cryptic polyadenylation in ALS/FTD

A metabolic atlas of mouse aging

Intersecting impact of CAG repeat and huntingtin knockout in stem cell-derived cortical neurons

Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data

Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons

Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer

Developmental basis of SHH medulloblastoma heterogeneity

Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma

Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

Dictionary of immune responses to cytokines at single-cell resolution

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Adaptive bias correction for improved subseasonal forecasting

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

Single cell metabolism: current and future trends

Cell environment shapes TDP-43 function with implications in neuronal and muscle disease

A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses

Sub-seasonal Prediction of Central European Summer Heatwaves with Linear and Random Forest Machine Learning Models

Predicting Central European summer heatwaves with Machine Learning

Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

Identifying Patterns of ALS Progression from Sparse Longitudinal Data

P04.04 Optimizing dasatinib for glioblastoma treatment

Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation