Area of research
Immunology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and Monoclonal and Polyclonal Antibodies Research.
MHC heterozygosity limits T cell receptor variability in CD4 T cells.
The basis of a more contagious 501Y.V1 variant of SARS-CoV-2
501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab <i>in vitro</i>.
Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation.
Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.
Author response: JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes
How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
JMJD6 Cleaves MePCE to Release P-TEFb
TCR signal strength controls thymic differentiation of iNKT cell subsets
Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7
B cells expressing the transcription factor T-bet drive lupus-like autoimmunity
Clipping of arginine-methylated histone tails by JMJD5 and JMJD7
Nicotine Impairs Macrophage Control of <i>Mycobacterium tuberculosis</i>
T-bet expressing B cells – Novel target for autoimmune therapies?
The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor
The domestic cat antibody response to feline herpesvirus-1 increases with age
Modulation of the Alternative Pathway of Complement by Murine Factor H–Related Proteins
T Cell Production of IFNγ in Response to TLR7/IL-12 Stimulates Optimal B Cell Responses to Viruses
Contamination of DNase Preparations Confounds Analysis of the Role of DNA in Alum-Adjuvanted Vaccines
Class II major histocompatibility complex mutant mice to study the germ-line bias of T-cell antigen receptors
Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity
CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs
N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes
Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen–Mismatched Grafts
A Rapid Method to Characterize Mouse IgG Antibodies and Isolate Native Antigen Binding IgG B Cell Hybridomas
Structural Basis of Chronic Beryllium Disease: Linking Allergic Hypersensitivity and Autoimmunity
TLR7, IFNγ, and T-bet: Their roles in the development of ABCs in female-biased autoimmunity
Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease