Area of research
Hepatology · Cancer Research
Research interest
Research interests include Liver physiology and pathology, Carcinogens and Genotoxicity Assessment, Liver Disease Diagnosis and Treatment, and Drug Transport and Resistance Mechanisms.
Gut-to-bile transfer of microbially amidated minor bile acids in patients with hepatopancreatobiliary disorders.
Targeting the ER stress sensor IRE1 protects the liver from fibrosis through the downregulation of the proteostasis factor P4HB/PDIA1.
Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety.
Selective genetic inactivation of Caspase 8 in hepatocytes ameliorates progression of MASH following Jnk deficiency.
Free Fatty acid-induced disruption of hepatic vitamin D metabolism impairs bone homeostasis in an in vitro 3D human liver-bone model.
Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease.
Enteronephrohepatic circulation of bile acids and therapeutic potential of systemic bile acid transporter inhibitors
A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development
Cannabidiol in Foods and Food Supplements: Evaluation of Health Risks and Health Claims.
Regulation of KIF23 by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma.
Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis
A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development.
Enteronephrohepatic circulation of bile acids and therapeutic potential of systemic bile acid transporter inhibitors.
Design of optimal concentrations for in vitro cytotoxicity experiments.
Characterization of children with early onset pediatric multiple sclerosis
Characterization of children with early onset pediatric multiple sclerosis.
The association between hair cortisol and burnout is moderated by age, psychosocial, and immunological markers.
Keap1 Deletion Rescues Cell Death Associated With Gpx4 Loss in Hepatocytes During Acute Liver Injury.
The long way from raw data to NAM-based information: Overview on data layers and processing steps.
Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA.
Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis.
Bats, bugs, and babies: why stringent guidelines are needed for cause-and-effect interpretation in epidemiological studies.
Fluoride intake during pregnancy: calculation of realistic exposure scenarios for individual risk assessment.
Changes of cognitive functions and proinflammatory cytokines across the lifespan in latent <i>Toxoplasma gondii</i> infection.
Improved identification of human hepatotoxic potential by summary variables of gene expression.
Comment to "The beneficial effect of combination therapy with sulfasalazine and valsartan in the treatment of ulcerative colitis [EXCLI Journal 2021;20:236-247]".
Developments in tattoo and tattoo removal toxicology.
Critical discussion of recently published claims of a causal relationship between bat decline and infant mortality.
Differential Protective Roles of c-Jun N-terminal Kinase-2 in Nonparenchymal Liver Cells and Hepatocytes During Cholestasis.
Follow-up of GSTM1, GSTT1, and NAT2 genotyped patients with knee or hip replacement.