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Myriam Gorospe

National Institutes of Health · US
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include RNA Research and Splicing, RNA modifications and cancer, Cancer-related molecular mechanisms research, and MicroRNA in disease regulation.
h-index
115
citations
52,782
works
647
NIH funding
primary concept
Biology
email

Recent publications

Plasticity of the mammalian integrated stress response
Nature 2025cited by 33position: middledoi
A guide to naming eukaryotic circular RNAs
Nature Cell Biology 2023cited by 108position: middledoi
A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion
Science Advances 2023cited by 18position: middledoi
Nuclear morphology is a deep learning biomarker of cellular senescence
Nature Aging 2022cited by 214position: middledoi
Hydroxychloroquine lowers Alzheimer’s disease and related dementias risk and rescues molecular phenotypes related to Alzheimer’s disease
Molecular Psychiatry 2022cited by 45position: middledoi
Transcriptomic analysis of human ALS skeletal muscle reveals a disease-specific pattern of dysregulated circRNAs
Aging 2022cited by 24position: middledoi
Personality traits are consistently associated with blood mitochondrial DNA copy number estimated from genome sequences in two genetic cohort studies
medRxiv 2022cited by 2position: middledoi
Proteomics in aging research: A roadmap to clinical, translational research
Aging Cell 2021cited by 136position: middledoi
The versatile role of HuR in Glioblastoma and its potential as a therapeutic target for a multi-pronged attack
Advanced Drug Delivery Reviews 2021cited by 25position: middledoi
Complex genetic signatures in immune cells underlie autoimmunity and inform therapy
Nature Genetics 2020cited by 1,229position: middledoi
circSamd4 represses myogenic transcriptional activity of PUR proteins
Nucleic Acids Research 2020cited by 109position: lastdoi
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
Journal of Clinical Investigation 2020cited by 57position: middledoi
NQO1 protects obese mice through improvements in glucose and lipid metabolism
npj Aging and Mechanisms of Disease 2020cited by 36position: middledoi
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
Nature Neuroscience 2019cited by 945position: middledoi
Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria
eLife 2019cited by 226position: middledoi
MIR100 host gene-encoded lncRNAs regulate cell cycle by modulating the interaction between HuR and its target mRNAs
Nucleic Acids Research 2018cited by 80position: middledoi
HuR regulates telomerase activity through TERC methylation
Nature Communications 2018cited by 49position: middledoi
Overexpression of the Cytokine BAFF and Autoimmunity Risk
New England Journal of Medicine 2017cited by 387position: middledoi
Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2016cited by 105position: middledoi
PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity
Nature Communications 2014cited by 172position: lastdoi
HuD Regulates Coding and Noncoding RNA to Induce APP→Aβ Processing
Cell Reports 2014cited by 108position: lastdoi
RNA-Binding Protein AUF1 Promotes Myogenesis by Regulating MEF2C Expression Levels
Molecular and Cellular Biology 2014cited by 59position: lastdoi
RNA binding protein HuR regulates the expression of ABCA1
Journal of Lipid Research 2014cited by 44position: middledoi
Novel RNA-binding Protein P311 Binds Eukaryotic Translation Initiation Factor 3 Subunit b (eIF3b) to Promote Translation of Transforming Growth Factor β1-3 (TGF-β1-3)
Journal of Biological Chemistry 2014cited by 33position: middledoi
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination
Nature Communications 2013cited by 458position: lastdoi
MicroRNA 33 Regulates Glucose Metabolism
Molecular and Cellular Biology 2013cited by 154position: middledoi
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation
Nature Neuroscience 2013cited by 149position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 9 papers (2013–2023) · 7 papers (2013–2020)Xiaoling Yang · Guangxi University6 papers (2013–2022)Je‐Hyun Yoon · University of Oklahoma Health Sciences Center6 papers (2013–2018)Luigi Ferrucci · Banyan Biomarkers (United States)3 papers (2019–2022)Kevin G. Becker · University of Tübingen3 papers (2014–2018)Ji Heon Noh · Medizinische Hochschule Hannover3 papers (2014–2020)Ioannis Grammatikakis · Center for Cancer Research3 papers (2014–2019) · 3 papers (2014–2022)Rafael de Cabo · National Institutes of Health3 papers (2013–2014)Carlos Fernández‐Hernando · New York University2 papers (2013–2014)Leigh Goedeke · New York University2 papers (2013–2014) · 2 papers (2022–2023)Alexey E. Lyashkov · University of Manchester2 papers (2019–2021)Subramanya Srikantan · The University of Texas Health Science Center at Houston2 papers (2013–2014)Kannanganattu V. Prasanth · University of Illinois Urbana-Champaign2 papers (2014–2018) · 2 papers (2020–2022) · 2 papers (2014–2014)Toshiko Tanaka · National Institutes of Health2 papers (2021–2022) · 2 papers (2014–2020)