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Tshepo Leeme

London School of Hygiene & Tropical Medicine · GB
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Area of research
Epidemiology · Infectious Diseases
Research interest
Research interests include Medicine, Cryptococcal meningitis, Meningitis, Amphotericin B, Human immunodeficiency virus (HIV), and Regimen.
h-index
citations
766
works
26
NIH funding
primary concept
email

Recent publications

Development and validation of quantitative PCR assays for HIV-associated cryptococcal meningitis in sub-Saharan Africa: a diagnostic accuracy study
The Lancet Microbe 2024cited by 15position: middledoi
Tracking Cryptococcal Meningitis to Monitor HIV Program Success During the Treat All Era: An Analysis of National Data in Botswana
Clinical Infectious Diseases 2024cited by 9position: middledoi
Computed Tomography of the Head Before Lumbar Puncture in Adults With Suspected Meningitis in High–HIV Prevalence Settings
Open Forum Infectious Diseases 2024cited by 3position: middledoi
Translating evidence into global impact: lessons for HIV research and policy development from the AMBITION trial
The Lancet Global Health 2023cited by 2position: middledoi
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis
LSTM Online Archive (Liverpool School of Tropical Medicine) 2022cited by 219position: middle
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial
The Lancet Global Health 2022cited by 29position: middledoi
Laboratory Evaluation of the VISITECT Advanced Disease Semiquantitative Point-of-Care CD4 Test
JAIDS Journal of Acquired Immune Deficiency Syndromes 2022cited by 18position: middledoi
Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting
Open Forum Infectious Diseases 2022cited by 8position: middledoi
Population pharmacokinetics of liposomal amphotericin B in adults with HIV-associated cryptococcal meningoencephalitis
Journal of Antimicrobial Chemotherapy 2022cited by 7position: middledoi
Reversal of CSF HIV-1 Escape during Treatment of HIV-Associated Cryptococcal Meningitis in Botswana
Biomedicines 2022cited by 5position: middledoi
Equity in clinical trials for HIV-associated cryptococcal meningitis: A systematic review of global representation and inclusion of patients and researchers
PLoS neglected tropical diseases 2021cited by 17position: middledoi
Evaluation of a Novel Semiquantitative Cryptococcal Antigen Lateral Flow Assay in Patients with Advanced HIV Disease
Journal of Clinical Microbiology 2020cited by 29position: middledoi
Utility of CD4 count measurement in the era of universal antiretroviral therapy: an analysis of routine laboratory data in Botswana
HIV Medicine 2020cited by 23position: firstdoi
Prevalence and Sequelae of Cryptococcal Antigenemia in Antiretroviral Therapy–Experienced Populations: An Evaluation of Reflex Cryptococcal Antigen Screening in Botswana
Clinical Infectious Diseases 2020cited by 19position: middledoi
Diagnostic Accuracy of the Biosynex CryptoPS Cryptococcal Antigen Semiquantitative Lateral Flow Assay in Patients with Advanced HIV Disease
Journal of Clinical Microbiology 2020cited by 17position: middledoi
Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100–200 Cells/µL in Botswana
Clinical Infectious Diseases 2020cited by 11position: middledoi
Differences in human immunodeficiency virus-1C viral load and drug resistance mutation between plasma and cerebrospinal fluid in patients with human immunodeficiency virus-associated cryptococcal meningitis in Botswana
Medicine 2020cited by 7position: middledoi
Mortality in adult patients with culture-positive and culture-negative meningitis in the Botswana national meningitis survey: a prevalent cohort study
The Lancet Infectious Diseases 2019cited by 30position: middledoi
Epidemiology of adult meningitis during antiretroviral therapy scale-up in southern Africa: Results from the Botswana national meningitis survey
Journal of Infection 2019cited by 19position: middledoi
Causes of Pediatric Meningitis in Botswana: Results From a 16-Year National Meningitis Audit
The Pediatric Infectious Disease Journal 2019cited by 12position: middledoi
Short-course High-dose Liposomal Amphotericin B for Human Immunodeficiency Virus–associated Cryptococcal Meningitis: A Phase 2 Randomized Controlled Trial
Clinical Infectious Diseases 2018cited by 82position: middledoi
High Mortality in HIV-Associated Cryptococcal Meningitis Patients Treated With Amphotericin B–Based Therapy Under Routine Care Conditions in Africa
Open Forum Infectious Diseases 2018cited by 40position: middledoi
Advanced Human Immunodeficiency Virus Disease in Botswana Following Successful Antiretroviral Therapy Rollout: Incidence of and Temporal Trends in Cryptococcal Meningitis
Clinical Infectious Diseases 2017cited by 63position: middledoi
HIV-Associated Cryptococcal Meningitis: Bridging the Gap Between Developed and Resource-Limited Settings
Current Clinical Microbiology Reports 2016cited by 33position: middledoi
The Impact of Systematic Point-of-Care Ultrasound on Management of Patients in a Resource-Limited Setting
American Journal of Tropical Medicine and Hygiene 2016cited by 24position: middledoi
AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: study protocol for a randomized controlled trial
Trials 2015cited by 25position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Joseph N Jarvis · University of London21 papers (2015–2024)Mark W. Tenforde · Centers for Disease Control and Prevention15 papers (2016–2024) · 12 papers (2017–2024) · 10 papers (2015–2022)Thomas S. Harrison · The Heart Research Institute9 papers (2015–2023)David S. Lawrence · University of London9 papers (2018–2024) · 8 papers (2020–2022) · 8 papers (2017–2024)Charles Muthoga · London School of Hygiene & Tropical Medicine7 papers (2018–2023) · 6 papers (2018–2020) · 6 papers (2018–2020)Hannah K Mitchell · Queen's University Belfast5 papers (2017–2020) · 5 papers (2017–2020) · 5 papers (2020–2022) · 4 papers (2017–2019) · 4 papers (2020–2020) · 4 papers (2017–2019)Síle F. Molloy · London School of Hygiene & Tropical Medicine4 papers (2015–2020) · 4 papers (2019–2024) · 4 papers (2017–2019)
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