Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Chromatin, Biology, Cell biology, Lamin, Nuclear lamina, and Heterochromatin.
Dynamics of microcompartment formation at the mitosis-to-G1 transition
Chromatin phase separation and nuclear shape fluctuations are correlated in a polymer model of the nucleus
Transcription shapes 3D chromatin organization by interacting with loop extrusion
CTCF and R-loops are boundaries of cohesin-mediated DNA looping
Transcription inhibition suppresses nuclear blebbing and rupture independently of nuclear rigidity
Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics
HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics
Loop extrusion: theory meets single-molecule experiments
Chromosome organization by one-sided and two-sided loop extrusion
Chromatin’s physical properties shape the nucleus and its functions
Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation
Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins
Facilitated dissociation of transcription factors from single DNA binding sites
Separate roles for chromatin and lamins in nuclear mechanics
Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells