Area of research
Physiology · Epidemiology
Research interest
Research interests include Adipose Tissue and Metabolism, Adipokines, Inflammation, and Metabolic Diseases, Lipid metabolism and biosynthesis, and Muscle Physiology and Disorders.
The transcription factor CUX1 exerts opposing roles in human and mouse adipocyte differentiation
Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant
The innate thermogenic capacity of brown adipose tissue develops independently of sympathetic signaling
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.
Transcriptional regulation of adipocyte lipolysis by IRF2BP2
PRDM16 regulates smooth muscle cell identity and atherosclerotic plaque composition.
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility
Shared and unique 3D genomic features of substance use disorders across multiple cell types
Control of murine brown adipocyte development by GATA6
Adipose-tissue plasticity in health and disease
ADRA1A-Gα<sub>q</sub> signalling potentiates adipocyte thermogenesis through CKB and TNAP.
Combined α- and β-adrenergic receptor activation triggers thermogenesis by the futile creatine cycle
Defining the lineage of thermogenic perivascular adipose tissue.
ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes
Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure
Identification of a mesenchymal progenitor cell hierarchy in adipose tissue
Identification of a mesenchymal progenitor cell hierarchy in adipose tissue.
Regeneration of fat cells from myofibroblasts during wound healing
Control of brown and beige fat development
Brown and Beige Fat: Physiological Roles beyond Heat Generation
Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity
Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch
p107 Is a Crucial Regulator for Determining the Adipocyte Lineage Fate Choices of Stem Cells
Brown and beige fat: development, function and therapeutic potential
EBF2 Determines and Maintains Brown Adipocyte Identity
Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity