Area of research
Immunology · Virology
Research interest
Research interests include Immune system, CD8, Biology, Immunology, Immunosenescence, and Medicine.
Aging and inflammation limit the induction of SARS-CoV-2–specific CD8+ T cell responses in severe COVID-19
Impact of cytomegalovirus infection on heterologous vaccine responsiveness
Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19
OC-8 Antiretroviral therapy restores naïve T cell frequencies and functionality in PLWH
Ageing Curtails the Diversity and Functionality of Nascent CD8+ T Cell Responses against SARS-CoV-2
Age differentially affects the maintenance of adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19
Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old
Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8+ T Cells in Elderly Humans
Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects
Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines
New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses
Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity
The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro
Altered basal lipid metabolism underlies the functional impairment of naive CD8 <sup>+</sup> T cells in elderly humans
The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T cells
Islet-reactive CD8 <sup>+</sup> T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors
Naïve CD8+ T-Cells Engage a Versatile Metabolic Program Upon Activation in Humans and Differ Energetically From Memory CD8+ T-Cells
Harnessing the Induction of CD8+ T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells
Cutting Edge: A Dual TLR2 and TLR7 Ligand Induces Highly Potent Humoral and Cell-Mediated Immune Responses
Priming of T cell responses 1
CMV and Immunosenescence: from basics to clinics