Axel Mogk

Allosteric control of the bacterial ClpC/ClpP protease and its hijacking by antibacterial peptides

Structure of the central Staphylococcus aureus AAA+ protease MecA/ClpC/ClpP

Balanced activities of Hsp70 and the ubiquitin proteasome system underlie cellular protein homeostasis

The beauty and complexity of the small heat shock proteins: a report on the proceedings of the fourth workshop on small heat shock proteins

Structural basis of aggregate binding by the AAA+ disaggregase ClpG

Structural basis of aggregate binding by the AAA+ disaggregase ClpG

Antibacterial peptide CyclomarinA creates toxicity by deregulating the Mycobacterium tuberculosis ClpC1–ClpP1P2 protease

Total Synthesis and Biological Evaluation of Modified Ilamycin Derivatives

The cytoprotective sequestration activity of small heat shock proteins is evolutionarily conserved

The Diverse Functions of Small Heat Shock Proteins in the Proteostasis Network

Resisting the Heat: Bacterial Disaggregases Rescue Cells From Devastating Protein Aggregation

Basic mechanism of the autonomous ClpG disaggregase

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

Processive extrusion of polypeptide loops by a Hsp100 disaggregase

The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

A recently isolated human commensal <i>Escherichia coli</i> ST10 clone member mediates enhanced thermotolerance and tetrathionate respiration on a P1 phage‐derived IncY plasmid

Publisher Correction: Processive extrusion of polypeptide loops by a Hsp100 disaggregase

Cellular Functions and Mechanisms of Action of Small Heat Shock Proteins

Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis

Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor

Toxic Activation of an AAA+ Protease by the Antibacterial Drug Cyclomarin A

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

ClpG Provides Increased Heat Resistance by Acting as Superior Disaggregase

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Cellular Handling of Protein Aggregates by Disaggregation Machines

A prion-like domain in Hsp42 drives chaperone-facilitated aggregation of misfolded proteins

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase

Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control

Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria